| 1. Journée | 14.09.1980 | Como Calcio | - | AS Roma | 0:1 | ||||
| 4. Journée | 05.10.1980 | AS Roma | - | Torino FC | 2:0 | ||||
| 5. Journée | 19.10.1980 | SSC Napoli | - | AS Roma | 4:0 | ||||
| 6. Journée | 26.10.1980 | Inter | - | AS Roma | 2:4 | ||||
| 7. Journée | 09.11.1980 | AS Roma | - | US Catanzaro | 0:0 | ||||
| 8. Journée | 23.11.1980 | Cagliari Calcio | - | AS Roma | 1:0 | ||||
| 9. Journée | 30.11.1980 | AS Roma | - | Udinese Calcio | 3:1 | ||||
| 10. Journée | 14.12.1980 | ACF Fiorentina | - | AS Roma | 1:1 | ||||
| 12. Journée | 28.12.1980 | AC Perugia | - | AS Roma | 1:1 | ||||
| 22. Journée | 22.03.1981 | US Catanzaro | - | AS Roma | 1:1 | ||||
| 26. Journée | 26.04.1981 | Ascoli Calcio | - | AS Roma | 0:0 | ||||
| 27. Journée | 03.05.1981 | AS Roma | - | AC Perugia | 5:0 | ||||
| 28. Journée | 10.05.1981 | Juventus | - | AS Roma | 0:0 | ||||
| 29. Journée | 17.05.1981 | AS Roma | - | AC Pistoiese | 1:0 | ||||
| 30. Journée | 24.05.1981 | US Avellino | - | AS Roma | 1:1 |
Italie