| 1. Journée | 06.08.2005 | Southampton FC | - | Wolverhampton Wanderers | 0:0 |  |
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| 2. Journée | 09.08.2005 | Luton Town | - | Southampton FC | 3:2 | |
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| 7. Journée | 10.09.2005 | Southampton FC | - | Queens Park Rangers | 1:1 | ||||
| 8. Journée | 13.09.2005 | Ipswich Town | - | Southampton FC | 2:2 |  |
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| 9. Journée | 18.09.2005 | Derby County | - | Southampton FC | 2:2 | |
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| 10. Journée | 24.09.2005 | Southampton FC | - | Plymouth Argyle | 0:0 | ||||
| 11. Journée | 28.09.2005 | Southampton FC | - | Reading FC | 0:0 | ||||
| 12. Journée | 01.10.2005 | Preston North End | - | Southampton FC | 1:1 | ||||
| 15. Journée | 22.10.2005 | Millwall FC | - | Southampton FC | 0:2 | ||||
| 16. Journée | 29.10.2005 | Southampton FC | - | Stoke City | 2:0 | ||||
| 19. Journée | 19.11.2005 | Southampton FC | - | Leeds United | 3:4 | |
Angleterre