| 1. Journée | 09.03.2025 | Miami FC | - | Detroit City FC | 0:2 | ||||
| 2. Journée | 15.03.2025 | Colorado Springs Switchbacks | - | Detroit City FC | 1:2 |  |
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| 3. Journée | 22.03.2025 | Detroit City FC | - | Birmingham Legion | 2:2 | |
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| 4. Journée | 29.03.2025 | Louisville City FC | - | Detroit City FC | 2:0 | ||||
| 5. Journée | 05.04.2025 | Detroit City FC | - | Monterey Bay FC | 0:0 |  |
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| 6. Journée | 13.04.2025 | Phoenix Rising | - | Detroit City FC | 2:3 | |
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| 7. Journée | 19.04.2025 | Detroit City FC | - | Rhode Island FC | 2:0 | |
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| 8. Journée | 04.05.2025 | Indy Eleven | - | Detroit City FC | 2:2 | |
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| 9. Journée | 11.05.2025 | Hartford Athletic | - | Detroit City FC | 0:0 | ||||
| 10. Journée | 18.05.2025 | Birmingham Legion | - | Detroit City FC | 1:1 |
Afrique du Sud