| 2. Journée | 02.04.2021 | Treaty United | - | Wexford FC | 1:0 |  |
|||
| 4. Journée | 16.04.2021 | Galway United | - | Treaty United | 1:1 | ||||
| 5. Journée | 23.04.2021 | Treaty United | - | Cork City | 2:1 |  |
|||
| 6. Journée | 30.04.2021 | Shelbourne FC | - | Treaty United | 2:2 |  |
|
||
| 7. Journée | 07.05.2021 | UC Dublin | - | Treaty United | 3:2 | ||||
| 8. Journée | 14.05.2021 | Treaty United | - | Athlone Town | 1:0 | ||||
| 9. Journée | 21.05.2021 | Cabinteely FC | - | Treaty United | 2:1 | |
|||
| 12. Journée | 19.06.2021 | Cobh Ramblers | - | Treaty United | 0:2 | |
|||
| 13. Journée | 25.06.2021 | Treaty United | - | Galway United | 0:1 | |
|||
| 14. Journée | 02.07.2021 | Cork City | - | Treaty United | 2:3 | ||||
| 16. Journée | 16.07.2021 | Treaty United | - | UC Dublin | 2:1 | ||||
| 17. Journée | 30.07.2021 | Athlone Town | - | Treaty United | 1:4 | ||||
| 18. Journée | 06.08.2021 | Treaty United | - | Cabinteely FC | 1:4 | |
 |
||
| 21. Journée | 03.09.2021 | Treaty United | - | Cobh Ramblers | 3:0 | ||||
| 22. Journée | 10.09.2021 | Galway United | - | Treaty United | 0:0 | ||||
| 23. Journée | 24.09.2021 | Treaty United | - | Cork City | 0:0 | ||||
| 24. Journée | 01.10.2021 | Shelbourne FC | - | Treaty United | 1:0 | ||||
| 27. Journée | 29.10.2021 | Cabinteely FC | - | Treaty United | 0:2 |
Irlande