| 2. Journée | 13.02.2022 | Sporting San Miguelito | - | Plaza Amador | 1:1 |  |
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| 8. Journée | 20.03.2022 | Veraguas United | - | Sporting San Miguelito | 1:2 | ||||
| 9. Journée | 26.03.2022 | San Francisco FC | - | Sporting San Miguelito | 0:1 | |
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| 16. Journée | 07.05.2022 | Potros del Este | - | Sporting San Miguelito | 0:3 |
Panama