| 2. Journée | 21.07.2022 | Tacuary | - | Cerro Porteño | 0:1 | ||||
| 3. Journée | 25.07.2022 | Cerro Porteño | - | Sol de América | 2:0 | ||||
| 7. Journée | 22.08.2022 | Cerro Porteño | - | Guaraní | 1:1 | ||||
| 8. Journée | 27.08.2022 | General Caballero DJLM | - | Cerro Porteño | 1:1 |  |
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| 9. Journée | 05.09.2022 | Cerro Porteño | - | Libertad | 1:0 |
Paraguay