| 2. Journée | 02.05.2021 | Rio Grande Valley FC | - | New Mexico United | 1:0 | ||||
| 2. Journée | 16.05.2021 | New Mexico United | - | Austin Bold | 3:1 |  |
|||
| 2. Journée | 22.05.2021 | Colorado Springs Switchbacks | - | New Mexico United | 1:3 | ||||
| 2. Journée | 30.05.2021 | New Mexico United | - | Loudoun United | 0:1 | ||||
| 3. Journée | 05.06.2021 | Real Monarchs SLC | - | New Mexico United | 0:1 | ||||
| 3. Journée | 13.06.2021 | New Mexico United | - | Austin Bold | 0:0 | ||||
| 3. Journée | 17.06.2021 | New Mexico United | - | San Antonio FC | 2:0 | ||||
| 3. Journée | 26.06.2021 | Colorado Springs Switchbacks | - | New Mexico United | 3:1 | ||||
| 3. Journée | 01.07.2021 | Real Monarchs SLC | - | New Mexico United | 3:2 | ||||
| 4. Journée | 04.07.2021 | El Paso Locomotive | - | New Mexico United | 2:1 | |
 |
||
| 4. Journée | 10.07.2021 | New Mexico United | - | Colorado Springs Switchbacks | 3:1 | ||||
| 4. Journée | 25.07.2021 | New Mexico United | - | El Paso Locomotive | 0:0 | ||||
| 5. Journée | 01.08.2021 | Tacoma Defiance | - | New Mexico United | 0:0 |
Jamaïque