| 1. Journée | 16.08.2024 | Leicester City U21 | - | Southampton FC U21 | 1:2 | ||||
| 3. Journée | 30.08.2024 | Southampton FC U21 | - | Tottenham Hotspur U21 | 2:1 | ||||
| 4. Journée | 20.09.2024 | Southampton FC U21 | - | Norwich City U21 | 2:3 | ||||
| 5. Journée | 27.09.2024 | West Bromwich Albion U21 | - | Southampton FC U21 | 1:1 | ||||
| 6. Journée | 04.10.2024 | Nottingham Forest U21 | - | Southampton FC U21 | 0:2 | ||||
| 7. Journée | 25.10.2024 | Southampton FC U21 | - | Crystal Palace U21 | 0:2 | ||||
| 9. Journée | 29.11.2024 | Stoke City U21 | - | Southampton FC U21 | 0:3 | ||||
| 10. Journée | 14.12.2024 | Manchester United U21 | - | Southampton FC U21 | 5:1 | ||||
| 14. Journée | 07.02.2025 | Southampton FC U21 | - | Liverpool FC U21 | 1:1 | ||||
| 16. Journée | 21.02.2025 | Southampton FC U21 | - | Sunderland AFC U21 | 3:3 | ||||
| 20. Journée | 11.04.2025 | Derby County U21 | - | Southampton FC U21 | 0:0 |
Angleterre