| 2. Journée | 25.07.2021 | Borac Banja Luka | - | Leotar Trebinje | 0:0 | ||||
| 3. Journée | 30.07.2021 | Sloboda Tuzla | - | Leotar Trebinje | 1:0 | ||||
| 6. Journée | 25.08.2021 | Leotar Trebinje | - | HŠK Posušje | 2:2 |  |
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| 7. Journée | 28.08.2021 | Velež Mostar | - | Leotar Trebinje | 2:1 | |
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| 8. Journée | 11.09.2021 | Leotar Trebinje | - | Zrinjski Mostar | 0:1 | ||||
| 9. Journée | 17.09.2021 | FK Sarajevo | - | Leotar Trebinje | 0:1 | ||||
| 10. Journée | 22.09.2021 | Leotar Trebinje | - | FK Rudar | 2:1 | |
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| 11. Journée | 26.09.2021 | Željezničar Sarajevo | - | Leotar Trebinje | 1:0 | ||||
| 12. Journée | 02.10.2021 | Leotar Trebinje | - | Radnik Bijeljina | 1:0 | ||||
| 13. Journée | 16.10.2021 | Leotar Trebinje | - | Borac Banja Luka | 1:1 | ||||
| 14. Journée | 23.10.2021 | Leotar Trebinje | - | Sloboda Tuzla | 1:1 | ||||
| 15. Journée | 31.10.2021 | FK Tuzla City | - | Leotar Trebinje | 4:0 | ||||
| 16. Journée | 06.11.2021 | Leotar Trebinje | - | Široki Brijeg | 1:3 |  |
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| 17. Journée | 21.11.2021 | HŠK Posušje | - | Leotar Trebinje | 1:0 | ||||
| 19. Journée | 03.12.2021 | Zrinjski Mostar | - | Leotar Trebinje | 6:2 | |
Bosnie-Herzégovine