| 1. Journée | 05.02.2022 | Montevideo City Torque | - | Cerro Largo | 1:1 | ||||
| 2. Journée | 14.02.2022 | Montevideo Wanderers | - | Cerro Largo | 1:0 |  |
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| 3. Journée | 19.02.2022 | Cerro Largo | - | Plaza Colonia | 0:5 | ||||
| 4. Journée | 25.02.2022 | Boston River | - | Cerro Largo | 3:0 | ||||
| 5. Journée | 05.03.2022 | River Plate | - | Cerro Largo | 1:1 | ||||
| 6. Journée | 22.03.2022 | Cerro Largo | - | Cerrito | 1:0 | ||||
| 7. Journée | 03.04.2022 | Fénix | - | Cerro Largo | 2:0 | ||||
| 8. Journée | 09.04.2022 | Cerro Largo | - | Defensor Sporting | 0:0 | ||||
| 10. Journée | 23.04.2022 | Cerro Largo | - | Nacional | 0:2 | ||||
| 13. Journée | 21.05.2022 | Rentistas | - | Cerro Largo | 2:0 | ||||
| 15. Journée | 04.06.2022 | Peñarol | - | Cerro Largo | 0:1 |
Uruguay