| tour des 16 | 29.09.2022 | Defensor Sporting | - | River Plate | 2:0 |  |
|||
| Quarts de finale | 04.10.2022 | Defensor Sporting | - | Liverpool | 3:0 | |
|||
| Demi-finales | 26.10.2022 | Progreso | - | Defensor Sporting | 1:1 | ||||
| Demi-finales | 04.11.2022 | Defensor Sporting | - | Progreso | 3:1 | |
|||
| Finale | 13.11.2022 | Defensor Sporting | - | La Luz | 1:0 |  |
Uruguay