| 4. Journée | 18.07.2020 | Speranţa Nisporeni | - | Dinamo-Auto | 1:2 | ||||
| 5. Journée | 22.07.2020 | FC Floreşti | - | Speranţa Nisporeni | 1:1 | ||||
| 7. Journée | 31.07.2020 | Dacia Buiucani | - | Speranţa Nisporeni | 0:3 | ||||
| 14. Journée | 16.10.2020 | Speranţa Nisporeni | - | FC Floreşti | 0:0 | ||||
| 16. Journée | 25.10.2020 | Speranţa Nisporeni | - | Dacia Buiucani | 0:0 | ||||
| 17. Journée | 31.10.2020 | Speranţa Nisporeni | - | FC Codru Lozova | 3:0 | ||||
| 18. Journée | 06.11.2020 | FC Sfîntul Gheorghe | - | Speranţa Nisporeni | 1:0 | ||||
| 19. Journée | 21.11.2020 | FC Sheriff | - | Speranţa Nisporeni | 3:0 |  |
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| 20. Journée | 25.11.2020 | Speranţa Nisporeni | - | FC Zimbru | 2:2 | |
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| 21. Journée | 20.02.2021 | FC Milsami | - | Speranţa Nisporeni | 3:0 | |
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| 27. Journée | 11.04.2021 | Speranţa Nisporeni | - | FC Sfîntul Gheorghe | 0:3 | ||||
| 29. Journée | 23.04.2021 | FC Zimbru | - | Speranţa Nisporeni | 6:0 |
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