| 1. Journée | 04.02.2018 | Progreso | - | Danubio | 1:1 | ||||
| 2. Journée | 10.02.2018 | Torque | - | Progreso | 0:3 | ||||
| 5. Journée | 04.03.2018 | Progreso | - | Nacional | 2:1 | ||||
| 6. Journée | 10.03.2018 | Progreso | - | CA Cerro | 0:1 | ||||
| 7. Journée | 17.03.2018 | Defensor Sporting | - | Progreso | 1:1 | ||||
| 8. Journée | 25.03.2018 | Progreso | - | Racing | 3:0 |  |
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| 9. Journée | 28.03.2018 | River Plate | - | Progreso | 4:2 | ||||
| 10. Journée | 31.03.2018 | Progreso | - | Montevideo Wanderers | 0:1 | ||||
| 11. Journée | 08.04.2018 | Liverpool | - | Progreso | 1:1 |  |
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| 13. Journée | 22.04.2018 | Boston River | - | Progreso | 3:2 | |
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| 15. Journée | 05.05.2018 | Atenas | - | Progreso | 0:6 |
Uruguay