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| 30.07.2021 | 17:00 | FK Mash'al Muborak | - | Surkhon Termez FK | 2:1 (0:0) | |
| 17:00 | Lokomotiv Tashkent | - | FC Nasaf | 2:0 (2:0) | ||
| 31.07.2021 | 17:00 | Pakhtakor Tashkent | - | Bunyodkor PFK | 1:0 (1:0) | |
| 17:00 | Andijon PFK | - | FK Turon | 1:1 (0:1) | ||
| 17:00 | So’g’diyona PFK | - | FC AGMK | 0:0 (0:0) | ||
| 01.08.2021 | 17:00 | Metallurg Bekobod | - | Qizilqum Zarafshon | 1:2 (0:0) | |
| 17:00 | FK Qo’qon 1912 | - | Navbahor Namangan | 1:2 (0:1) |
| » Classement | équipe recevante | à l'extérieur | Premier tour | Second tour |
| # | Équipe | M. | G. | N. | P. | Buts | Diff. | Pts. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Pakhtakor Tashkent | 13 | 11 | 2 | 0 | 26:6 | 20 | 35 |
| 2 |
|
FC AGMK | 13 | 8 | 2 | 3 | 19:14 | 5 | 26 |
| 3 |
|
So’g’diyona PFK | 13 | 6 | 6 | 1 | 18:10 | 8 | 24 |
| 4 |
|
FC Nasaf | 13 | 7 | 2 | 4 | 22:12 | 10 | 23 |
| 5 |
|
Qizilqum Zarafshon | 13 | 6 | 5 | 2 | 15:10 | 5 | 23 |
| 6 |
|
Bunyodkor PFK | 13 | 5 | 3 | 5 | 19:13 | 6 | 18 |
| 7 |
|
Lokomotiv Tashkent | 13 | 5 | 3 | 5 | 18:16 | 2 | 18 |
| 8 |
|
Navbahor Namangan | 13 | 4 | 5 | 4 | 13:12 | 1 | 17 |
| 9 |
|
Metallurg Bekobod | 13 | 5 | 1 | 7 | 14:17 | -3 | 16 |
| 10 |
|
FK Qo’qon 1912 | 13 | 4 | 3 | 6 | 13:16 | -3 | 15 |
| 11 |
|
FK Mash'al Muborak | 13 | 3 | 3 | 7 | 11:21 | -10 | 12 |
| 12 |
|
FK Turon | 13 | 1 | 5 | 7 | 7:17 | -10 | 8 |
| 13 |
|
Andijon PFK | 13 | 2 | 2 | 9 | 10:22 | -12 | 8 |
| 14 |
|
Surkhon Termez FK | 13 | 2 | 2 | 9 | 7:26 | -19 | 8 |
| Champions League | |
| Champions League Quali. | |
| Relégation | |
| Relégation |
