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| Classement | équipe recevante | à l'extérieur | Premier tour | Second tour | 1. Mi-temps | » 2. Mi-temps |
| 1 | |||||||||
| # | Équipe | M. | G. | N. | P. | Buts | Diff. | Pts. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Columbus Crew (M) | 30 | 17 | 8 | 5 | 41:21 | 20 | 59 |
| 2 |
|
Inter Miami CF | 30 | 15 | 10 | 5 | 39:22 | 17 | 55 |
| 3 |
|
FC Cincinnati | 30 | 14 | 11 | 5 | 34:21 | 13 | 53 |
| 4 |
|
Philadelphia Union | 30 | 14 | 7 | 9 | 31:27 | 4 | 49 |
| 5 |
|
Orlando City | 30 | 12 | 10 | 8 | 28:23 | 5 | 46 |
| 6 |
|
New York RB | 30 | 11 | 11 | 8 | 28:24 | 4 | 44 |
| 7 |
|
Atlanta United FC | 30 | 11 | 9 | 10 | 28:28 | 0 | 42 |
| 8 |
|
Charlotte FC | 30 | 9 | 13 | 8 | 21:18 | 3 | 40 |
| 9 |
|
Chicago Fire | 31 | 10 | 8 | 13 | 26:27 | -1 | 38 |
| 10 |
|
Toronto FC | 31 | 9 | 7 | 15 | 22:40 | -18 | 34 |
| 11 |
|
New York City FC | 30 | 9 | 6 | 15 | 21:27 | -6 | 33 |
| 12 |
|
D.C. United | 30 | 9 | 6 | 15 | 21:31 | -10 | 33 |
| 13 |
|
CF Montréal | 30 | 8 | 9 | 13 | 22:32 | -10 | 33 |
| 14 |
|
Nashville SC | 30 | 6 | 10 | 14 | 13:23 | -10 | 28 |
| 15 |
|
New England Revolution | 30 | 3 | 5 | 22 | 12:41 | -29 | 14 |
| 2 | |||||||||
| # | Équipe | M. | G. | N. | P. | Buts | Diff. | Pts. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Los Angeles Galaxy | 31 | 14 | 13 | 4 | 42:22 | 20 | 55 |
| 2 |
|
Colorado Rapids | 30 | 16 | 6 | 8 | 34:24 | 10 | 54 |
| 3 |
|
Los Angeles FC | 30 | 14 | 7 | 9 | 28:24 | 4 | 49 |
| 4 |
|
Vancouver Whitecaps | 30 | 13 | 10 | 7 | 30:21 | 9 | 49 |
| 5 |
|
Portland Timbers | 30 | 13 | 6 | 11 | 37:28 | 9 | 45 |
| 6 |
|
Seattle Sounders | 30 | 12 | 9 | 9 | 25:18 | 7 | 45 |
| 7 |
|
Minnesota United FC | 30 | 11 | 10 | 9 | 28:24 | 4 | 43 |
| 8 |
|
Real Salt Lake | 30 | 9 | 13 | 8 | 30:26 | 4 | 40 |
| 9 |
|
FC Dallas | 30 | 9 | 11 | 10 | 29:28 | 1 | 38 |
| 10 |
|
Houston Dynamo | 30 | 8 | 12 | 10 | 24:24 | 0 | 36 |
| 11 |
|
Sporting Kansas City | 31 | 8 | 12 | 11 | 30:36 | -6 | 36 |
| 12 |
|
Austin FC | 30 | 8 | 10 | 12 | 19:23 | -4 | 34 |
| 13 |
|
St. Louis City SC | 30 | 6 | 10 | 14 | 19:36 | -17 | 28 |
| 14 |
|
San Jose Earthquakes | 30 | 6 | 7 | 17 | 18:41 | -23 | 25 |
| Play-off | |
| Play-off |
