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| Classement | équipe recevante | à l'extérieur | Premier tour | Second tour | » 1. Mi-temps | 2. Mi-temps |
| 1 | |||||||||
| # | Équipe | M. | G. | N. | P. | Buts | Diff. | Pts. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Columbus Crew (M) | 30 | 13 | 12 | 5 | 21:10 | 11 | 51 |
| 2 |
|
New York RB | 30 | 12 | 12 | 6 | 19:15 | 4 | 48 |
| 3 |
|
Inter Miami CF | 30 | 12 | 11 | 7 | 29:22 | 7 | 47 |
| 4 |
|
Philadelphia Union | 30 | 13 | 7 | 10 | 26:20 | 6 | 46 |
| 5 |
|
Nashville SC | 30 | 12 | 7 | 11 | 18:23 | -5 | 43 |
| 6 |
|
New York City FC | 30 | 10 | 13 | 7 | 22:16 | 6 | 43 |
| 7 |
|
Toronto FC | 31 | 9 | 12 | 10 | 16:15 | 1 | 39 |
| 8 |
|
FC Cincinnati | 30 | 8 | 14 | 8 | 18:18 | 0 | 38 |
| 9 |
|
Orlando City | 30 | 10 | 7 | 13 | 22:22 | 0 | 37 |
| 10 |
|
New England Revolution | 30 | 9 | 9 | 12 | 20:23 | -3 | 36 |
| 11 |
|
D.C. United | 30 | 9 | 9 | 12 | 23:30 | -7 | 36 |
| 12 |
|
Charlotte FC | 30 | 6 | 18 | 6 | 15:15 | 0 | 36 |
| 13 |
|
CF Montréal | 30 | 8 | 10 | 12 | 19:29 | -10 | 34 |
| 14 |
|
Atlanta United FC | 30 | 6 | 14 | 10 | 12:16 | -4 | 32 |
| 15 |
|
Chicago Fire | 31 | 4 | 12 | 15 | 10:27 | -17 | 24 |
| 2 | |||||||||
| # | Équipe | M. | G. | N. | P. | Buts | Diff. | Pts. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Houston Dynamo | 30 | 11 | 15 | 4 | 19:9 | 10 | 48 |
| 2 |
|
Los Angeles FC | 30 | 13 | 7 | 10 | 26:17 | 9 | 46 |
| 3 |
|
Real Salt Lake | 30 | 12 | 10 | 8 | 30:19 | 11 | 46 |
| 4 |
|
Seattle Sounders | 30 | 11 | 11 | 8 | 20:16 | 4 | 44 |
| 5 |
|
Portland Timbers | 30 | 12 | 7 | 11 | 26:25 | 1 | 43 |
| 6 |
|
Vancouver Whitecaps | 30 | 11 | 8 | 11 | 20:21 | -1 | 41 |
| 7 |
|
St. Louis City SC | 30 | 10 | 11 | 9 | 24:21 | 3 | 41 |
| 8 |
|
Colorado Rapids | 30 | 10 | 11 | 9 | 24:26 | -2 | 41 |
| 9 |
|
Los Angeles Galaxy | 31 | 10 | 11 | 10 | 21:24 | -3 | 41 |
| 10 |
|
Minnesota United FC | 30 | 10 | 8 | 12 | 22:24 | -2 | 38 |
| 11 |
|
FC Dallas | 30 | 7 | 15 | 8 | 20:21 | -1 | 36 |
| 12 |
|
Sporting Kansas City | 31 | 8 | 11 | 12 | 19:22 | -3 | 35 |
| 13 |
|
Austin FC | 30 | 7 | 13 | 10 | 13:19 | -6 | 34 |
| 14 |
|
San Jose Earthquakes | 30 | 6 | 11 | 13 | 19:28 | -9 | 29 |
| Play-off | |
| Play-off |
