 |
 |
|
| 20.08.2021 | 17:45 | Progreso | - | Montevideo City Torque | 1:4 (1:2) | |
| 20:00 | Fénix | - | Montevideo Wanderers | 2:1 (0:1) | ||
| 21.08.2021 | 15:15 | Liverpool | - | Cerrito | 3:0 (2:0) | |
| 17:30 | Deportivo Maldonado | - | Boston River | 0:2 (0:1) | ||
| 20:00 | River Plate | - | Nacional | 2:0 (1:0) | ||
| 22.08.2021 | 17:30 | Plaza Colonia | - | Rentistas | 2:0 (1:0) | |
| 20:00 | Sud América | - | Peñarol | 1:1 (0:1) | ||
| 22:30 | Cerro Largo | - | Villa Española | 3:1 (1:0) |
| » Classement | équipe recevante | à l'extérieur | Premier tour | Second tour |
| # | Équipe | M. | G. | N. | P. | Buts | Diff. | Pts. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Plaza Colonia | 15 | 11 | 3 | 1 | 20:7 | 13 | 36 |
| 2 |
|
Nacional | 15 | 9 | 2 | 4 | 23:14 | 9 | 29 |
| 3 |
|
Peñarol | 15 | 7 | 7 | 1 | 22:10 | 12 | 28 |
| 4 |
|
Liverpool | 15 | 8 | 3 | 4 | 38:20 | 18 | 27 |
| 5 |
|
River Plate | 15 | 7 | 5 | 3 | 27:20 | 7 | 26 |
| 6 |
|
Montevideo City Torque | 15 | 8 | 1 | 6 | 26:19 | 7 | 25 |
| 7 |
|
Fénix | 15 | 6 | 3 | 6 | 20:22 | -2 | 21 |
| 8 |
|
Cerro Largo | 15 | 6 | 2 | 7 | 20:22 | -2 | 20 |
| 9 |
|
Cerrito | 15 | 5 | 4 | 6 | 14:15 | -1 | 19 |
| 10 |
|
Sud América | 15 | 5 | 3 | 7 | 15:22 | -7 | 18 |
| 11 |
|
Montevideo Wanderers | 15 | 5 | 2 | 8 | 12:16 | -4 | 17 |
| 12 |
|
Rentistas | 15 | 4 | 4 | 7 | 12:21 | -9 | 16 |
| 13 |
|
Boston River | 15 | 3 | 5 | 7 | 14:19 | -5 | 14 |
| 14 |
|
Deportivo Maldonado | 15 | 3 | 5 | 7 | 11:22 | -11 | 14 |
| 15 |
|
Progreso | 15 | 2 | 5 | 8 | 13:26 | -13 | 11 |
| 16 |
|
Villa Española | 15 | 1 | 6 | 8 | 14:26 | -12 | 9 |
| Play-off |
