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| 30.04.2022 | 19:30 | Sakaryaspor | - | Kahramanmaraşspor | 1:0 (1:0) | |
| 01.05.2022 | 14:00 | Adıyamanspor | - | Çorum FK | 2:2 (0:1) | |
| 14:00 | Afjet Afyonspor | - | Sarıyer SK | 4:2 (3:2) | ||
| 14:00 | Diyarbekirspor | - | Bayburt İl Özel İdare | 0:1 (0:1) | ||
| 14:00 | Ergene Velimeşe | - | Sivas Belediyespor | 2:0 (2:0) | ||
| 14:00 | Etimesgut Belediyespor | - | Ankaraspor | 0:2 (0:1) | ||
| 14:00 | 1461 Trabzon FK | - | Somaspor | 3:1 (1:1) | ||
| 14:00 | Inegölspor | - | Vanspor FK | 2:3 (1:1) | ||
| 14:00 | Niğde Anadolu FK | - | Bodrum FK | 1:1 (1:1) | ||
| 14:00 | Turgutluspor | - | Serik Belediyespor | 1:2 (0:1) |
| » Classement | équipe recevante | à l'extérieur | Premier tour | Second tour |
| # | Équipe | M. | G. | N. | P. | Buts | Diff. | Pts. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Sakaryaspor | 37 | 25 | 9 | 3 | 75:23 | 52 | 84 |
| 2 |
|
1461 Trabzon FK | 37 | 22 | 7 | 8 | 63:32 | 31 | 73 |
| 3 |
|
Bodrum FK | 37 | 21 | 9 | 7 | 60:25 | 35 | 72 |
| 4 |
|
Sivas Belediyespor | 37 | 19 | 9 | 9 | 65:34 | 31 | 66 |
| 5 |
|
Bayburt İl Özel İdare | 37 | 18 | 9 | 10 | 49:35 | 14 | 63 |
| 6 |
|
Vanspor FK | 37 | 17 | 12 | 8 | 51:44 | 7 | 63 |
| 7 |
|
Afjet Afyonspor | 37 | 18 | 8 | 11 | 65:41 | 24 | 62 |
| 8 |
|
Çorum FK | 37 | 17 | 11 | 9 | 55:39 | 16 | 62 |
| 9 |
|
Ankaraspor | 37 | 14 | 12 | 11 | 53:40 | 13 | 54 |
| 10 |
|
Somaspor | 37 | 15 | 7 | 15 | 50:50 | 0 | 52 |
| 11 |
|
Inegölspor | 37 | 14 | 8 | 15 | 51:54 | -3 | 50 |
| 12 |
|
Etimesgut Belediyespor | 37 | 12 | 11 | 14 | 45:53 | -8 | 47 |
| 13 |
|
Serik Belediyespor | 37 | 12 | 6 | 19 | 46:55 | -9 | 42 |
| 14 |
|
Diyarbekirspor | 37 | 12 | 5 | 20 | 33:43 | -10 | 41 |
| 15 |
|
Sarıyer SK | 37 | 10 | 10 | 17 | 47:58 | -11 | 40 |
| 16 |
|
Adıyamanspor | 37 | 11 | 5 | 21 | 45:70 | -25 | 38 |
| 17 |
|
Ergene Velimeşe | 37 | 10 | 5 | 22 | 38:71 | -33 | 35 |
| 18 |
|
Turgutluspor | 37 | 8 | 10 | 19 | 30:62 | -32 | 34 |
| 19 |
|
Niğde Anadolu FK | 37 | 7 | 8 | 22 | 43:80 | -37 | 29 |
| 20 |
|
Kahramanmaraşspor | 37 | 4 | 7 | 26 | 23:78 | -55 | 19 |
| Promotion | |
| Play-off | |
| Relégation |
