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| 21.01.2022 | 11:00 | Zonguldak Kömürspor | - | Pendikspor | 2:3 (0:2) | |
| 22.01.2022 | Kastamonuspor | - | Uşakspor | pas disputer | ||
| 10:30 | Pazarspor | - | Nazilli Belediyespor | 1:0 (0:0) | ||
| 11:00 | 1922 Konyaspor | - | Isparta 32 SK | 0:4 (0:2) | ||
| 11:00 | Bucaspor 1928 | - | Akhisar Belediyespor | 2:2 (1:1) | ||
| 11:00 | 24 Erzincanspor | - | Tarsus Idman Yurdu | 2:1 (0:1) | ||
| 11:00 | Amed SK | - | Kırşehir Belediyespor | 1:1 (1:0) | ||
| 11:00 | Kırklarelispor | - | Ankara Demirspor | 1:0 (1:0) | ||
| 11:00 | Şanlıurfaspor | - | Eskişehirspor | 2:0 (0:0) |
| » Classement | équipe recevante | à l'extérieur | Premier tour | Second tour |
| # | Équipe | M. | G. | N. | P. | Buts | Diff. | Pts. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Pendikspor | 18 | 13 | 3 | 2 | 27:14 | 13 | 42 |
| 2 |
|
Bucaspor 1928 | 19 | 9 | 4 | 6 | 30:23 | 7 | 31 |
| 3 |
|
Amed SK | 19 | 8 | 6 | 5 | 25:21 | 4 | 30 |
| 4 |
|
Kırklarelispor | 19 | 6 | 10 | 3 | 26:17 | 9 | 28 |
| 5 |
|
Isparta 32 SK | 19 | 8 | 4 | 7 | 21:16 | 5 | 28 |
| 6 |
|
Nazilli Belediyespor | 19 | 7 | 7 | 5 | 17:15 | 2 | 28 |
| 7 |
|
Ankara Demirspor | 19 | 7 | 6 | 6 | 20:18 | 2 | 27 |
| 8 |
|
24 Erzincanspor | 18 | 7 | 5 | 6 | 27:21 | 6 | 26 |
| 9 |
|
Kırşehir Belediyespor | 19 | 6 | 8 | 5 | 21:17 | 4 | 26 |
| 10 |
|
Şanlıurfaspor | 19 | 6 | 8 | 5 | 22:20 | 2 | 26 |
| 11 |
|
Uşakspor | 18 | 6 | 7 | 5 | 16:18 | -2 | 25 |
| 12 |
|
Pazarspor | 19 | 8 | 1 | 10 | 25:29 | -4 | 25 |
| 13 |
|
Akhisar Belediyespor | 19 | 6 | 5 | 8 | 22:26 | -4 | 23 |
| 14 |
|
Zonguldak Kömürspor | 19 | 6 | 4 | 9 | 22:29 | -7 | 22 |
| 15 |
|
Tarsus Idman Yurdu | 19 | 5 | 6 | 8 | 15:18 | -3 | 21 |
| 16 |
|
1922 Konyaspor | 19 | 4 | 7 | 8 | 24:28 | -4 | 19 |
| 17 |
|
Karacabey Belediyespor | 18 | 5 | 1 | 12 | 23:33 | -10 | 16 |
| 18 |
|
Eskişehirspor | 19 | 4 | 4 | 11 | 18:38 | -20 | 13 |
| 19 |
|
Kastamonuspor | 0 | 0 | 0 | 0 | 0:0 | 0 | 0 |
| Promotion | |
| Play-off | |
| Relégation |
