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| 01.05.2021 | 12:30 | Eskişehirspor | - | Bursaspor | 1:5 (1:1) | |
| 15:00 | Adana Demirspor | - | Balıkesirspor | 3:0 (0:0) | ||
| 15:00 | Altınordu FK | - | Tuzlaspor | 3:2 (2:1) | ||
| 15:00 | Bandırmaspor | - | Adanaspor | 3:2 (1:0) | ||
| 15:00 | Giresunspor | - | Akhisar Belediyespor | 3:0 (2:0) | ||
| 15:00 | İstanbulspor AŞ | - | Boluspor | 1:1 (0:0) | ||
| 15:00 | Keçiörengücü | - | Menemen Belediyespor | 4:1 (1:1) | ||
| 15:00 | Samsunspor | - | Ankaraspor | 3:1 (1:0) | ||
| 15:00 | Ümraniyespor | - | Altay Izmir | 0:1 (0:0) |
| » Classement | équipe recevante | à l'extérieur | Premier tour | Second tour |
| # | Équipe | M. | G. | N. | P. | Buts | Diff. | Pts. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Adana Demirspor | 33 | 20 | 7 | 6 | 60:26 | 34 | 67 |
| 2 |
|
Giresunspor | 33 | 20 | 7 | 6 | 52:24 | 28 | 67 |
| 3 |
|
Samsunspor | 33 | 19 | 10 | 4 | 56:30 | 26 | 67 |
| 4 |
|
İstanbulspor AŞ | 33 | 18 | 7 | 8 | 60:34 | 26 | 61 |
| 5 |
|
Altay Izmir | 33 | 19 | 3 | 11 | 62:36 | 26 | 60 |
| 6 |
|
Altınordu FK | 33 | 16 | 9 | 8 | 53:45 | 8 | 57 |
| 7 |
|
Keçiörengücü | 33 | 16 | 7 | 10 | 46:28 | 18 | 55 |
| 8 |
|
Ümraniyespor | 33 | 14 | 8 | 11 | 45:42 | 3 | 50 |
| 9 |
|
Tuzlaspor | 33 | 14 | 5 | 14 | 45:51 | -6 | 47 |
| 10 |
|
Bursaspor | 33 | 14 | 4 | 15 | 56:54 | 2 | 46 |
| 11 |
|
Bandırmaspor | 33 | 12 | 6 | 15 | 45:47 | -2 | 42 |
| 12 |
|
Boluspor | 33 | 11 | 6 | 16 | 35:41 | -6 | 39 |
| 13 |
|
Balıkesirspor | 33 | 9 | 8 | 16 | 35:48 | -13 | 35 |
| 14 |
|
Adanaspor | 33 | 9 | 7 | 17 | 44:53 | -9 | 34 |
| 15 |
|
Menemen Belediyespor | 33 | 7 | 13 | 13 | 37:58 | -21 | 34 |
| 16 |
|
Akhisar Belediyespor | 33 | 8 | 5 | 20 | 35:58 | -23 | 29 |
| 17 |
|
Ankaraspor | 33 | 6 | 8 | 19 | 33:59 | -26 | 26 |
| 18 |
|
Eskişehirspor | 33 | 1 | 8 | 24 | 23:88 | -65 | 8 |
| Promotion | |
| Play-off | |
| Relégation |
