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| 17.04.2021 | 15:00 | Keçiörengücü | - | Tuzlaspor | 0:1 (0:1) | |
| 18:00 | Adana Demirspor | - | Giresunspor | 3:0 (3:0) | ||
| 18.04.2021 | 12:30 | Eskişehirspor | - | Balıkesirspor | 0:3 (0:2) | |
| 15:00 | Akhisar Belediyespor | - | Altınordu FK | 1:1 (0:1) | ||
| 18:00 | İstanbulspor AŞ | - | Menemen Belediyespor | 4:0 (1:0) | ||
| 19.04.2021 | 12:30 | Ümraniyespor | - | Ankaraspor | 4:3 (1:2) | |
| 15:00 | Altay Izmir | - | Adanaspor | 4:1 (2:1) | ||
| 15:00 | Bandırmaspor | - | Boluspor | 2:3 (1:2) | ||
| 18:00 | Samsunspor | - | Bursaspor | 4:1 (2:0) |
| » Classement | équipe recevante | à l'extérieur | Premier tour | Second tour |
| # | Équipe | M. | G. | N. | P. | Buts | Diff. | Pts. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Giresunspor | 31 | 19 | 6 | 6 | 49:24 | 25 | 63 |
| 2 |
|
Adana Demirspor | 31 | 18 | 7 | 6 | 54:26 | 28 | 61 |
| 3 |
|
Samsunspor | 31 | 17 | 10 | 4 | 51:29 | 22 | 61 |
| 4 |
|
Altay Izmir | 31 | 18 | 3 | 10 | 61:34 | 27 | 57 |
| 5 |
|
İstanbulspor AŞ | 31 | 17 | 6 | 8 | 57:32 | 25 | 57 |
| 6 |
|
Altınordu FK | 31 | 15 | 8 | 8 | 50:43 | 7 | 53 |
| 7 |
|
Keçiörengücü | 31 | 14 | 7 | 10 | 40:26 | 14 | 49 |
| 8 |
|
Ümraniyespor | 31 | 13 | 8 | 10 | 43:41 | 2 | 47 |
| 9 |
|
Tuzlaspor | 31 | 14 | 5 | 12 | 43:45 | -2 | 47 |
| 10 |
|
Bursaspor | 31 | 13 | 4 | 14 | 50:51 | -1 | 43 |
| 11 |
|
Bandırmaspor | 31 | 11 | 6 | 14 | 40:42 | -2 | 39 |
| 12 |
|
Boluspor | 31 | 11 | 5 | 15 | 34:38 | -4 | 38 |
| 13 |
|
Balıkesirspor | 31 | 9 | 8 | 14 | 34:43 | -9 | 35 |
| 14 |
|
Adanaspor | 31 | 9 | 7 | 15 | 42:48 | -6 | 34 |
| 15 |
|
Menemen Belediyespor | 31 | 6 | 13 | 12 | 34:53 | -19 | 31 |
| 16 |
|
Akhisar Belediyespor | 31 | 7 | 5 | 19 | 33:55 | -22 | 26 |
| 17 |
|
Ankaraspor | 31 | 5 | 8 | 18 | 29:54 | -25 | 23 |
| 18 |
|
Eskişehirspor | 31 | 1 | 8 | 22 | 21:81 | -60 | 8 |
| Promotion | |
| Play-off | |
| Relégation |
