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| 03.04.2021 | 12:30 | Tuzlaspor | - | Samsunspor | 0:2 (0:0) | |
| 15:00 | Giresunspor | - | İstanbulspor AŞ | 0:0 (0:0) | ||
| 15:00 | Ankaraspor | - | Akhisar Belediyespor | 4:2 (2:1) | ||
| 18:00 | Adana Demirspor | - | Keçiörengücü | 2:0 (1:0) | ||
| 04.04.2021 | 12:30 | Altınordu FK | - | Eskişehirspor | 6:3 (4:0) | |
| 12:30 | Boluspor | - | Adanaspor | 1:2 (1:1) | ||
| 15:00 | Menemen Belediyespor | - | Ümraniyespor | 1:1 (0:0) | ||
| 18:00 | Balıkesirspor | - | Bandırmaspor | 2:1 (1:1) | ||
| 05.04.2021 | 18:00 | Bursaspor | - | Altay Izmir | 1:3 (0:1) |
| » Classement | équipe recevante | à l'extérieur | Premier tour | Second tour |
| # | Équipe | M. | G. | N. | P. | Buts | Diff. | Pts. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Giresunspor | 28 | 17 | 6 | 5 | 42:20 | 22 | 57 |
| 2 |
|
Samsunspor | 28 | 15 | 9 | 4 | 44:26 | 18 | 54 |
| 3 |
|
Altay Izmir | 28 | 17 | 2 | 9 | 55:30 | 25 | 53 |
| 4 |
|
Adana Demirspor | 28 | 15 | 7 | 6 | 47:24 | 23 | 52 |
| 5 |
|
Altınordu FK | 28 | 15 | 7 | 6 | 46:36 | 10 | 52 |
| 6 |
|
İstanbulspor AŞ | 28 | 14 | 6 | 8 | 49:30 | 19 | 48 |
| 7 |
|
Keçiörengücü | 28 | 13 | 7 | 8 | 34:20 | 14 | 46 |
| 8 |
|
Tuzlaspor | 28 | 12 | 5 | 11 | 36:41 | -5 | 41 |
| 9 |
|
Bursaspor | 28 | 12 | 4 | 12 | 46:44 | 2 | 40 |
| 10 |
|
Bandırmaspor | 28 | 11 | 5 | 12 | 35:35 | 0 | 38 |
| 11 |
|
Ümraniyespor | 28 | 10 | 8 | 10 | 33:36 | -3 | 38 |
| 12 |
|
Boluspor | 28 | 9 | 5 | 14 | 29:32 | -3 | 32 |
| 13 |
|
Balıkesirspor | 28 | 8 | 8 | 12 | 30:40 | -10 | 32 |
| 14 |
|
Adanaspor | 28 | 8 | 7 | 13 | 37:41 | -4 | 31 |
| 15 |
|
Menemen Belediyespor | 28 | 6 | 11 | 11 | 30:45 | -15 | 29 |
| 16 |
|
Akhisar Belediyespor | 28 | 7 | 4 | 17 | 29:48 | -19 | 25 |
| 17 |
|
Ankaraspor | 28 | 4 | 7 | 17 | 22:47 | -25 | 19 |
| 18 |
|
Eskişehirspor | 28 | 1 | 8 | 19 | 19:68 | -49 | 8 |
| Promotion | |
| Play-off | |
| Relégation |
