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| 02.09.2022 | 16:30 | MŠK Žilina | - | FK Železiarne Podbrezová | 0:1 (0:0) | |
| 03.09.2022 | 18:00 | Dukla Banská Bystrica | - | Slovan Bratislava | 0:1 (0:0) | |
| 18:00 | FC DAC 1904 | - | MFK Zemplín Michalovce | 1:0 (0:0) | ||
| 18:00 | Tatran Liptovský Mikuláš | - | MFK Skalica | 0:0 (0:0) | ||
| 18:00 | Zlaté Moravce | - | AS Trenčín | 1:0 (1:0) | ||
| 04.09.2022 | 17:30 | MFK Ružomberok | - | Spartak Trnava | 3:2 (3:1) |
| » Classement | équipe recevante | à l'extérieur | Premier tour | Second tour |
| # | Équipe | M. | G. | N. | P. | Buts | Diff. | Pts. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Slovan Bratislava | 9 | 7 | 1 | 1 | 23:7 | 16 | 22 |
| 2 |
|
FK Železiarne Podbrezová | 9 | 4 | 5 | 0 | 15:8 | 7 | 17 |
| 3 |
|
Spartak Trnava | 9 | 4 | 3 | 2 | 17:10 | 7 | 15 |
| 4 |
|
FC DAC 1904 | 9 | 4 | 3 | 2 | 13:8 | 5 | 15 |
| 5 |
|
MFK Ružomberok | 9 | 3 | 5 | 1 | 13:10 | 3 | 14 |
| 6 |
|
MŠK Žilina | 9 | 3 | 3 | 3 | 11:9 | 2 | 12 |
| 7 |
|
AS Trenčín | 9 | 3 | 2 | 4 | 7:12 | -5 | 11 |
| 8 |
|
MFK Skalica | 9 | 2 | 4 | 3 | 8:12 | -4 | 10 |
| 9 |
|
Dukla Banská Bystrica | 9 | 3 | 0 | 6 | 12:19 | -7 | 9 |
| 10 |
|
MFK Zemplín Michalovce | 9 | 2 | 2 | 5 | 10:17 | -7 | 8 |
| 11 |
|
Zlaté Moravce | 9 | 1 | 4 | 4 | 8:15 | -7 | 7 |
| 12 |
|
Tatran Liptovský Mikuláš | 9 | 0 | 4 | 5 | 7:17 | -10 | 4 |
| Play-off | |
| Relégation |
