 |
 |
|
|
| 17.09.2021 | 17:00 | Spartak Trnava | - | ŠKF Sereď | 2:0 (1:0) | |
| 18.09.2021 | 18:00 | AS Trenčín | - | FK Senica | 3:3 (1:2) | |
| 18:00 | MFK Ružomberok | - | FC DAC 1904 | 1:2 (0:1) | ||
| 18:00 | MFK Zemplín Michalovce | - | Zlaté Moravce | 2:1 (2:1) | ||
| 18:00 | Tatran Liptovský Mikuláš | - | FK Pohronie | 5:1 (2:0) | ||
| 19.09.2021 | 17:00 | Slovan Bratislava | - | MŠK Žilina | 2:2 (2:2) |
| » Classement | équipe recevante | à l'extérieur | Premier tour | Second tour |
| # | Équipe | M. | G. | N. | P. | Buts | Diff. | Pts. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Slovan Bratislava | 8 | 5 | 2 | 1 | 17:7 | 10 | 17 |
| 2 |
|
Spartak Trnava | 8 | 5 | 2 | 1 | 14:4 | 10 | 17 |
| 3 |
|
MŠK Žilina | 8 | 4 | 2 | 2 | 15:9 | 6 | 14 |
| 4 |
|
AS Trenčín | 8 | 3 | 4 | 1 | 14:9 | 5 | 13 |
| 5 |
|
FK Senica | 8 | 3 | 4 | 1 | 10:10 | 0 | 13 |
| 6 |
|
FC DAC 1904 | 8 | 3 | 3 | 2 | 12:10 | 2 | 12 |
| 7 |
|
MFK Ružomberok | 8 | 2 | 5 | 1 | 8:7 | 1 | 11 |
| 8 |
|
MFK Zemplín Michalovce | 8 | 3 | 1 | 4 | 11:12 | -1 | 10 |
| 9 |
|
ŠKF Sereď | 8 | 2 | 2 | 4 | 6:10 | -4 | 8 |
| 10 |
|
Tatran Liptovský Mikuláš | 8 | 2 | 0 | 6 | 11:19 | -8 | 6 |
| 11 |
|
Zlaté Moravce | 8 | 1 | 2 | 5 | 6:16 | -10 | 5 |
| 12 |
|
FK Pohronie | 8 | 1 | 1 | 6 | 5:16 | -11 | 4 |
| Play-off | |
| Relégation |
