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| 10.11.2022 | 19:00 | Fortuna Köln | - | 1. FC Köln II | 2:2 (0:0) | |
| 11.11.2022 | 19:00 | FC Schalke 04 II | - | Alemannia Aachen | 0:0 (0:0) | |
| 12.11.2022 | 14:00 | Preußen Münster | - | Wuppertaler SV | 0:1 (0:0) | |
| 14:00 | Fortuna Düsseldorf II | - | Rot Weiss Ahlen | 5:0 (3:0) | ||
| 14:00 | 1. FC Düren | - | SG Wattenscheid 09 | 1:2 (1:0) | ||
| 14:00 | Rot-Weiß Oberhausen | - | SC Wiedenbrück | 1:0 (0:0) | ||
| 14:00 | 1. FC Kaan-Marienborn | - | 1. FC Bocholt | 3:0 (2:0) | ||
| 14:00 | SV Rödinghausen | - | Bor. Mönchengladbach II | 0:1 (0:0) | ||
| 14:00 | SV Lippstadt 08 | - | SV 19 Straelen | 3:1 (1:0) |
| # | Équipe | M. | G. | N. | P. | Buts | Diff. | Pts. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Preußen Münster | 16 | 11 | 2 | 3 | 40:16 | 24 | 35 |
| 2 |
|
Bor. Mönchengladbach II | 16 | 8 | 5 | 3 | 29:19 | 10 | 29 |
| 3 |
|
Wuppertaler SV | 16 | 8 | 4 | 4 | 29:19 | 10 | 28 |
| 4 |
|
Alemannia Aachen | 16 | 8 | 4 | 4 | 26:20 | 6 | 28 |
| 5 |
|
1. FC Kaan-Marienborn | 16 | 8 | 3 | 5 | 25:24 | 1 | 27 |
| 6 |
|
SV Rödinghausen | 16 | 8 | 2 | 6 | 29:15 | 14 | 26 |
| 7 |
|
FC Schalke 04 II | 16 | 7 | 4 | 5 | 34:23 | 11 | 25 |
| 8 |
|
Rot-Weiß Oberhausen | 16 | 7 | 4 | 5 | 29:28 | 1 | 25 |
| 9 |
|
SV Lippstadt 08 | 16 | 8 | 1 | 7 | 29:30 | -1 | 25 |
| 10 |
|
Fortuna Köln | 16 | 7 | 4 | 5 | 19:21 | -2 | 25 |
| 11 |
|
Fortuna Düsseldorf II | 16 | 7 | 1 | 8 | 29:33 | -4 | 22 |
| 12 |
|
Rot Weiss Ahlen | 16 | 5 | 4 | 7 | 28:31 | -3 | 19 |
| 13 |
|
1. FC Düren | 16 | 6 | 1 | 9 | 19:30 | -11 | 19 |
| 14 |
|
1. FC Köln II | 16 | 5 | 3 | 8 | 25:34 | -9 | 18 |
| 15 |
|
1. FC Bocholt | 16 | 5 | 3 | 8 | 26:37 | -11 | 18 |
| 16 |
|
SC Wiedenbrück | 16 | 4 | 5 | 7 | 22:20 | 2 | 17 |
| 17 |
|
SG Wattenscheid 09 | 16 | 3 | 3 | 10 | 18:40 | -22 | 12 |
| 18 |
|
SV 19 Straelen | 16 | 2 | 1 | 13 | 11:27 | -16 | 7 |
| Promotion | |
| Relégation | |
| Relégation |
