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| 09.04.2022 | 13:00 | Blau-Weiß 90 Berlin | - | Brandenburger SC Süd | 2:0 (2:0) | |
| 14:00 | RSV Eintracht 1949 | - | Victoria Seelow | 2:2 (2:0) | ||
| 14:00 | Torgelower FC Greif | - | Ludwigsfelder FC | 0:0 (0:0) | ||
| 10.04.2022 | 13:00 | SFC Stern 1900 | - | SC Staaken | 1:1 (1:0) | |
| 14:00 | 1. FC Lok Stendal | - | Greifswalder FC | 1:2 (0:0) | ||
| 14:00 | Hansa Rostock II | - | TSG Neustrelitz | 1:2 (0:1) | ||
| 14:00 | Eintracht Mahlsdorf | - | Hertha Zehlendorf | 0:0 (0:0) | ||
| 14:00 | MSV 1919 Neuruppin | - | FC Mecklenburg Schwerin | 3:2 (2:0) | ||
| 14:00 | MSV Pampow | - | CFC Hertha 06 | 1:2 (1:1) |
| » Classement | équipe recevante | à l'extérieur | Premier tour | Second tour |
| # | Équipe | M. | G. | N. | P. | Buts | Diff. | Pts. | ∅ | |
|---|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Greifswalder FC | 21 | 14 | 4 | 3 | 38:21 | 17 | 46 | 2.19 |
| 2 |
|
Blau-Weiß 90 Berlin | 22 | 15 | 1 | 6 | 49:30 | 19 | 46 | 2.09 |
| 3 |
|
Rostocker FC | 21 | 14 | 1 | 6 | 55:19 | 36 | 43 | 2.05 |
| 4 |
|
Hertha Zehlendorf | 22 | 13 | 3 | 6 | 43:21 | 22 | 42 | 1.91 |
| 5 |
|
CFC Hertha 06 | 22 | 12 | 6 | 4 | 38:25 | 13 | 42 | 1.91 |
| 6 |
|
SC Staaken | 22 | 11 | 7 | 4 | 41:21 | 20 | 40 | 1.82 |
| 7 |
|
TSG Neustrelitz | 21 | 10 | 6 | 5 | 26:18 | 8 | 36 | 1.71 |
| 8 |
|
RSV Eintracht 1949 | 22 | 9 | 10 | 3 | 38:25 | 13 | 37 | 1.68 |
| 9 |
|
Eintracht Mahlsdorf | 22 | 9 | 6 | 7 | 37:28 | 9 | 33 | 1.50 |
| 10 |
|
Torgelower FC Greif | 21 | 8 | 5 | 8 | 42:27 | 15 | 29 | 1.38 |
| 11 |
|
Hansa Rostock II | 22 | 7 | 6 | 9 | 38:39 | -1 | 27 | 1.23 |
| 12 |
|
FC Mecklenburg Schwerin | 22 | 8 | 3 | 11 | 31:40 | -9 | 27 | 1.23 |
| 13 |
|
MSV Pampow | 22 | 7 | 5 | 10 | 32:41 | -9 | 26 | 1.18 |
| 14 |
|
Ludwigsfelder FC | 22 | 7 | 5 | 10 | 26:35 | -9 | 26 | 1.18 |
| 15 |
|
MSV 1919 Neuruppin | 22 | 5 | 6 | 11 | 24:47 | -23 | 21 | 0.95 |
| 16 |
|
Brandenburger SC Süd | 22 | 4 | 4 | 14 | 18:36 | -18 | 16 | 0.73 |
| 17 |
|
Victoria Seelow | 22 | 3 | 4 | 15 | 25:61 | -36 | 13 | 0.59 |
| 18 |
|
1. FC Lok Stendal | 22 | 3 | 4 | 15 | 22:59 | -37 | 13 | 0.59 |
| 19 |
|
SFC Stern 1900 | 22 | 1 | 8 | 13 | 21:51 | -30 | 11 | 0.50 |
| Promotion | |
| Relégation | |
| Relégation |
