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| 13.11.2021 | 14:00 | FV Ravensburg | - | TSV Ilshofen | 1:1 (0:1) | |
| 14:00 | SGV Freiberg | - | Göppinger SV | 2:0 (1:0) | ||
| 14:00 | Stuttgarter Kickers | - | FC Nöttingen | 3:2 (2:0) | ||
| 14:00 | TSG Backnang | - | 1. FC Bruchsal | 2:3 (1:0) | ||
| 14:00 | Sportfreunde Dorfmerkingen | - | SV Oberachern | 1:4 (1:3) | ||
| 14:30 | FC-Astoria Walldorf II | - | FV Lörrach-Brombach | 3:3 (2:2) | ||
| 14:30 | SSV Reutlingen | - | FSV 08 Bietigheim-Bissingen | 2:2 (1:0) | ||
| 15:30 | FC 08 Villingen | - | Freiburger FC | 2:1 (0:1) | ||
| 15:30 | SV Linx | - | 1. CfR Pforzheim | 0:3 (0:2) | ||
| 14.11.2021 | 14:30 | 1. FC Rielasingen-Arlen | - | Neckarsulmer Sport-Union | 0:1 (0:0) |
| » Classement | équipe recevante | à l'extérieur | Premier tour | Second tour |
| # | Équipe | M. | G. | N. | P. | Buts | Diff. | Pts. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
SGV Freiberg | 17 | 12 | 4 | 1 | 55:14 | 41 | 40 |
| 2 |
|
Stuttgarter Kickers | 17 | 12 | 2 | 3 | 36:10 | 26 | 38 |
| 3 |
|
FC 08 Villingen | 17 | 10 | 2 | 5 | 33:20 | 13 | 32 |
| 4 |
|
TSG Backnang | 17 | 10 | 1 | 6 | 37:24 | 13 | 31 |
| 5 |
|
FSV 08 Bietigheim-Bissingen | 17 | 8 | 4 | 5 | 35:19 | 16 | 28 |
| 6 |
|
1. FC Rielasingen-Arlen | 17 | 8 | 4 | 5 | 21:18 | 3 | 28 |
| 7 |
|
Göppinger SV | 17 | 8 | 4 | 5 | 27:25 | 2 | 28 |
| 8 |
|
FC-Astoria Walldorf II | 17 | 8 | 3 | 6 | 26:25 | 1 | 27 |
| 9 |
|
SSV Reutlingen | 17 | 7 | 5 | 5 | 27:22 | 5 | 26 |
| 10 |
|
1. CfR Pforzheim | 17 | 8 | 2 | 7 | 26:24 | 2 | 26 |
| 11 |
|
FV Ravensburg | 17 | 6 | 7 | 4 | 36:26 | 10 | 25 |
| 12 |
|
SV Oberachern | 17 | 8 | 1 | 8 | 29:31 | -2 | 25 |
| 13 |
|
FC Nöttingen | 17 | 7 | 2 | 8 | 34:29 | 5 | 23 |
| 14 |
|
Neckarsulmer Sport-Union | 17 | 6 | 4 | 7 | 24:29 | -5 | 22 |
| 15 |
|
SV Linx | 17 | 5 | 4 | 8 | 15:36 | -21 | 19 |
| 16 |
|
Sportfreunde Dorfmerkingen | 17 | 4 | 4 | 9 | 20:39 | -19 | 16 |
| 17 |
|
1. FC Bruchsal | 17 | 4 | 2 | 11 | 18:41 | -23 | 14 |
| 18 |
|
Freiburger FC | 17 | 3 | 4 | 10 | 18:31 | -13 | 13 |
| 19 |
|
TSV Ilshofen | 17 | 2 | 3 | 12 | 16:44 | -28 | 9 |
| 20 |
|
FV Lörrach-Brombach | 17 | 1 | 4 | 12 | 12:38 | -26 | 7 |
| Promotion | |
| Relégation | |
| Relégation |
