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| 28.05.2022 | 18:00 | ASWH Ido-Ambacht | - | VV Noordwijk | 1:5 (1:2) | |
| 18:00 | De Treffers | - | HHC Hardenberg | 1:1 (1:0) | ||
| 18:00 | Excelsior Maassluis | - | SV Spakenburg | 4:0 (3:0) | ||
| 18:00 | Koninklijke HFC | - | VV Katwijk | 4:1 (1:1) | ||
| 18:00 | IJsselmeervogels | - | GVVV | 3:0 (1:0) | ||
| 18:00 | Quick Boys | - | Jong FC Volendam | 1:3 (1:1) | ||
| 18:00 | Rijnsburgse Boys | - | Sparta Rotterdam (J) | 2:1 (0:1) | ||
| 18:00 | SVV Scheveningen | - | Kozakken Boys | 2:1 (0:1) | ||
| 18:00 | TEC VV | - | Amsterdamsche FC | 2:2 (2:1) |
| # | Équipe | M. | G. | N. | P. | Buts | Diff. | Pts. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
VV Katwijk | 33 | 21 | 5 | 7 | 70:34 | 36 | 68 |
| 2 |
|
HHC Hardenberg | 33 | 18 | 5 | 10 | 55:42 | 13 | 59 |
| 3 |
|
Koninklijke HFC | 33 | 16 | 9 | 8 | 53:36 | 17 | 57 |
| 4 |
|
Rijnsburgse Boys | 33 | 17 | 4 | 12 | 62:41 | 21 | 55 |
| 5 |
|
Sparta Rotterdam (J) | 33 | 16 | 6 | 11 | 56:48 | 8 | 54 |
| 6 |
|
Amsterdamsche FC | 33 | 14 | 9 | 10 | 59:49 | 10 | 51 |
| 7 |
|
VV Noordwijk | 33 | 15 | 6 | 12 | 49:45 | 4 | 51 |
| 8 |
|
SVV Scheveningen | 33 | 13 | 10 | 10 | 42:43 | -1 | 49 |
| 9 |
|
Excelsior Maassluis | 33 | 14 | 5 | 14 | 49:52 | -3 | 47 |
| 10 |
|
SV Spakenburg | 33 | 13 | 7 | 13 | 62:61 | 1 | 46 |
| 11 |
|
Quick Boys | 33 | 12 | 8 | 13 | 42:49 | -7 | 44 |
| 12 |
|
Jong FC Volendam | 33 | 13 | 3 | 17 | 63:64 | -1 | 42 |
| 13 |
|
IJsselmeervogels | 33 | 13 | 3 | 17 | 44:46 | -2 | 42 |
| 14 |
|
TEC VV | 33 | 11 | 9 | 13 | 43:58 | -15 | 42 |
| 15 |
|
De Treffers | 33 | 12 | 5 | 16 | 38:48 | -10 | 41 |
| 16 |
|
Kozakken Boys | 33 | 8 | 10 | 15 | 43:59 | -16 | 34 |
| 17 |
|
GVVV | 33 | 8 | 7 | 18 | 40:53 | -13 | 31 |
| 18 |
|
ASWH Ido-Ambacht | 33 | 5 | 5 | 23 | 35:77 | -42 | 20 |
| Relégation | |
| Relégation | |
| Relégation |
