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| 23.04.2022 | 14:00 | TEC VV | - | SV Spakenburg | 2:0 (2:0) | |
| 14:30 | GVVV | - | SVV Scheveningen | 0:2 (0:1) | ||
| 14:30 | VV Noordwijk | - | VV Katwijk | 2:0 (1:0) | ||
| 15:00 | ASWH Ido-Ambacht | - | Sparta Rotterdam (J) | 0:4 (0:3) | ||
| 15:00 | IJsselmeervogels | - | Kozakken Boys | 4:0 (3:0) | ||
| 15:00 | Jong FC Volendam | - | HHC Hardenberg | 3:4 (0:2) | ||
| 15:00 | Quick Boys | - | Koninklijke HFC | 0:4 (0:3) | ||
| 15:30 | Amsterdamsche FC | - | Rijnsburgse Boys | 1:3 (0:1) | ||
| 18:00 | De Treffers | - | Excelsior Maassluis | 2:0 (1:0) |
| # | Équipe | M. | G. | N. | P. | Buts | Diff. | Pts. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
VV Katwijk | 27 | 17 | 5 | 5 | 54:27 | 27 | 56 |
| 2 |
|
Koninklijke HFC | 27 | 15 | 7 | 5 | 46:27 | 19 | 52 |
| 3 |
|
HHC Hardenberg | 27 | 15 | 4 | 8 | 45:35 | 10 | 49 |
| 4 |
|
Sparta Rotterdam (J) | 27 | 14 | 5 | 8 | 48:41 | 7 | 47 |
| 5 |
|
Rijnsburgse Boys | 27 | 14 | 3 | 10 | 55:34 | 21 | 45 |
| 6 |
|
Amsterdamsche FC | 27 | 12 | 6 | 9 | 49:38 | 11 | 42 |
| 7 |
|
VV Noordwijk | 27 | 12 | 5 | 10 | 38:36 | 2 | 41 |
| 8 |
|
Quick Boys | 27 | 11 | 8 | 8 | 37:36 | 1 | 41 |
| 9 |
|
SVV Scheveningen | 27 | 10 | 9 | 8 | 34:35 | -1 | 39 |
| 10 |
|
De Treffers | 27 | 11 | 3 | 13 | 31:34 | -3 | 36 |
| 11 |
|
SV Spakenburg | 27 | 10 | 5 | 12 | 47:49 | -2 | 35 |
| 12 |
|
IJsselmeervogels | 27 | 11 | 2 | 14 | 36:39 | -3 | 35 |
| 13 |
|
Excelsior Maassluis | 27 | 10 | 5 | 12 | 38:46 | -8 | 35 |
| 14 |
|
TEC VV | 27 | 9 | 7 | 11 | 36:48 | -12 | 34 |
| 15 |
|
Jong FC Volendam | 27 | 9 | 3 | 15 | 49:53 | -4 | 30 |
| 16 |
|
Kozakken Boys | 27 | 6 | 8 | 13 | 31:49 | -18 | 26 |
| 17 |
|
GVVV | 27 | 4 | 7 | 16 | 25:47 | -22 | 19 |
| 18 |
|
ASWH Ido-Ambacht | 27 | 5 | 4 | 18 | 29:54 | -25 | 19 |
| Relégation | |
| Relégation | |
| Relégation |
