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| 11.04.2008 | 20:00 | BV Veendam | - | RKC Waalwijk | 0:1 (0:0) | |
| 20:00 | SC Cambuur | - | Helmond Sport | 5:1 (3:1) | ||
| 20:00 | HFC Haarlem | - | MVV | 0:0 (0:0) | ||
| 20:00 | FC Volendam | - | FC Dordrecht | 2:0 (0:0) | ||
| 20:00 | FC Zwolle | - | FC Emmen | 1:1 (0:1) | ||
| 20:00 | FC Eindhoven | - | AGOVV | 4:1 (2:1) | ||
| 20:00 | FC Den Bosch | - | Stormvogels Telstar | 3:0 (1:0) | ||
| 20:00 | Fortuna Sittard | - | ADO Den Haag | 2:2 (0:1) | ||
| 20:00 | RBC Roosendaal | - | TOP Oss | 0:1 (0:1) | ||
| 20:00 | FC Omniworld | - | Go Ahead Eagles | 0:4 (0:0) |
| » Classement | équipe recevante | à l'extérieur | Premier tour | Second tour |
| # | Équipe | M. | G. | N. | P. | Buts | Diff. | Pts. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
FC Volendam | 37 | 21 | 11 | 5 | 89:46 | 43 | 74 |
| 2 |
|
RKC Waalwijk | 37 | 21 | 11 | 5 | 82:43 | 39 | 74 |
| 3 |
|
FC Den Bosch | 37 | 21 | 7 | 9 | 61:36 | 25 | 70 |
| 4 |
|
FC Zwolle | 37 | 17 | 13 | 7 | 68:42 | 26 | 64 |
| 5 |
|
MVV | 37 | 16 | 11 | 10 | 64:48 | 16 | 59 |
| 6 |
|
ADO Den Haag | 37 | 16 | 10 | 11 | 58:49 | 9 | 58 |
| 7 |
|
Helmond Sport | 37 | 17 | 7 | 13 | 53:50 | 3 | 58 |
| 8 |
|
TOP Oss | 37 | 14 | 10 | 13 | 55:60 | -5 | 52 |
| 9 |
|
Go Ahead Eagles | 37 | 16 | 2 | 19 | 57:61 | -4 | 50 |
| 10 |
|
FC Emmen | 37 | 13 | 11 | 13 | 58:72 | -14 | 50 |
| 11 |
|
RBC Roosendaal | 37 | 13 | 10 | 14 | 45:47 | -2 | 49 |
| 12 |
|
FC Omniworld | 37 | 11 | 14 | 12 | 55:50 | 5 | 47 |
| 13 |
|
FC Dordrecht | 37 | 11 | 11 | 15 | 58:52 | 6 | 44 |
| 14 |
|
BV Veendam | 37 | 11 | 14 | 12 | 55:64 | -9 | 44 |
| 15 |
|
Stormvogels Telstar | 37 | 13 | 4 | 20 | 39:50 | -11 | 43 |
| 16 |
|
Fortuna Sittard | 37 | 10 | 10 | 17 | 47:67 | -20 | 40 |
| 17 |
|
SC Cambuur | 37 | 10 | 8 | 19 | 48:66 | -18 | 38 |
| 18 |
|
AGOVV | 37 | 11 | 5 | 21 | 61:97 | -36 | 35 |
| 19 |
|
FC Eindhoven | 37 | 8 | 8 | 21 | 48:80 | -32 | 32 |
| 20 |
|
HFC Haarlem | 37 | 5 | 13 | 19 | 36:57 | -21 | 28 |
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