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| 29.02.2008 | 20:00 | SC Cambuur | - | RKC Waalwijk | 2:0 (1:0) | |
| 20:00 | FC Volendam | - | Fortuna Sittard | 2:3 (2:1) | ||
| 20:00 | MVV | - | BV Veendam | 1:1 (1:1) | ||
| 20:00 | Go Ahead Eagles | - | Helmond Sport | 1:2 (0:1) | ||
| 20:00 | AGOVV | - | FC Emmen | 4:5 (1:2) | ||
| 20:00 | RBC Roosendaal | - | ADO Den Haag | 0:1 (0:1) | ||
| 20:00 | TOP Oss | - | FC Dordrecht | 1:1 (0:0) | ||
| 20:00 | FC Omniworld | - | FC Den Bosch | 1:0 (0:0) | ||
| 02.03.2008 | 14:30 | FC Eindhoven | - | FC Zwolle | 1:2 (1:1) | |
| 24.03.2008 | 13:00 | HFC Haarlem | - | Stormvogels Telstar | 0:1 (0:0) |
| » Classement | équipe recevante | à l'extérieur | Premier tour | Second tour |
| # | Équipe | M. | G. | N. | P. | Buts | Diff. | Pts. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
RKC Waalwijk | 30 | 16 | 10 | 4 | 69:38 | 31 | 58 |
| 2 |
|
FC Zwolle | 30 | 16 | 10 | 4 | 62:33 | 29 | 58 |
| 3 |
|
FC Volendam | 30 | 14 | 11 | 5 | 68:41 | 27 | 53 |
| 4 |
|
FC Den Bosch | 30 | 16 | 5 | 9 | 48:35 | 13 | 53 |
| 5 |
|
ADO Den Haag | 30 | 13 | 8 | 9 | 48:42 | 6 | 47 |
| 6 |
|
Helmond Sport | 30 | 14 | 5 | 11 | 44:39 | 5 | 47 |
| 7 |
|
MVV | 30 | 13 | 8 | 9 | 46:43 | 3 | 47 |
| 8 |
|
Go Ahead Eagles | 30 | 14 | 1 | 15 | 49:53 | -4 | 43 |
| 9 |
|
RBC Roosendaal | 30 | 10 | 10 | 10 | 37:37 | 0 | 40 |
| 10 |
|
TOP Oss | 30 | 10 | 10 | 10 | 46:51 | -5 | 40 |
| 11 |
|
FC Emmen | 30 | 10 | 10 | 10 | 49:60 | -11 | 40 |
| 12 |
|
FC Dordrecht | 30 | 9 | 10 | 11 | 52:43 | 9 | 37 |
| 13 |
|
Stormvogels Telstar | 30 | 11 | 4 | 15 | 33:42 | -9 | 37 |
| 14 |
|
FC Omniworld | 30 | 7 | 13 | 10 | 46:40 | 6 | 34 |
| 15 |
|
BV Veendam | 30 | 7 | 14 | 9 | 48:56 | -8 | 32 |
| 16 |
|
Fortuna Sittard | 30 | 8 | 8 | 14 | 38:49 | -11 | 32 |
| 17 |
|
SC Cambuur | 30 | 7 | 8 | 15 | 40:56 | -16 | 29 |
| 18 |
|
AGOVV | 30 | 9 | 5 | 16 | 51:77 | -26 | 29 |
| 19 |
|
HFC Haarlem | 30 | 5 | 12 | 13 | 34:45 | -11 | 27 |
| 20 |
|
FC Eindhoven | 30 | 7 | 6 | 17 | 39:67 | -28 | 27 |
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