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| 15.02.2008 | 20:00 | FC Emmen | - | FC Den Bosch | 0:3 (0:1) | |
| 20:00 | Stormvogels Telstar | - | Helmond Sport | 2:0 (1:0) | ||
| 20:00 | RKC Waalwijk | - | FC Dordrecht | 4:1 (3:1) | ||
| 20:00 | MVV | - | RBC Roosendaal | 1:1 (0:0) | ||
| 20:00 | FC Eindhoven | - | SC Cambuur | 2:1 (1:0) | ||
| 20:00 | AGOVV | - | BV Veendam | 5:0 (2:0) | ||
| 20:00 | TOP Oss | - | FC Zwolle | 2:4 (2:1) | ||
| 20:00 | FC Omniworld | - | Fortuna Sittard | 1:1 (0:1) | ||
| 17.02.2008 | 12:30 | Go Ahead Eagles | - | ADO Den Haag | 1:2 (0:1) | |
| 14:30 | HFC Haarlem | - | FC Volendam | 2:2 (1:0) |
| » Classement | équipe recevante | à l'extérieur | Premier tour | Second tour |
| # | Équipe | M. | G. | N. | P. | Buts | Diff. | Pts. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
RKC Waalwijk | 28 | 16 | 10 | 2 | 67:33 | 34 | 58 |
| 2 |
|
FC Zwolle | 28 | 14 | 10 | 4 | 53:32 | 21 | 52 |
| 3 |
|
FC Volendam | 28 | 13 | 11 | 4 | 63:36 | 27 | 50 |
| 4 |
|
FC Den Bosch | 28 | 15 | 5 | 8 | 45:33 | 12 | 50 |
| 5 |
|
MVV | 28 | 13 | 7 | 8 | 45:35 | 10 | 46 |
| 6 |
|
ADO Den Haag | 28 | 12 | 7 | 9 | 46:41 | 5 | 43 |
| 7 |
|
Go Ahead Eagles | 28 | 14 | 1 | 13 | 47:48 | -1 | 43 |
| 8 |
|
Helmond Sport | 28 | 12 | 5 | 11 | 40:38 | 2 | 41 |
| 9 |
|
RBC Roosendaal | 28 | 10 | 10 | 8 | 37:34 | 3 | 40 |
| 10 |
|
TOP Oss | 28 | 10 | 9 | 9 | 44:48 | -4 | 39 |
| 11 |
|
FC Dordrecht | 28 | 9 | 8 | 11 | 50:41 | 9 | 35 |
| 12 |
|
FC Emmen | 28 | 8 | 10 | 10 | 42:55 | -13 | 34 |
| 13 |
|
Stormvogels Telstar | 28 | 10 | 3 | 15 | 28:38 | -10 | 33 |
| 14 |
|
FC Omniworld | 28 | 6 | 12 | 10 | 44:39 | 5 | 30 |
| 15 |
|
BV Veendam | 28 | 7 | 12 | 9 | 43:51 | -8 | 30 |
| 16 |
|
AGOVV | 28 | 9 | 4 | 15 | 43:68 | -25 | 28 |
| 17 |
|
FC Eindhoven | 28 | 7 | 6 | 15 | 38:62 | -24 | 27 |
| 18 |
|
HFC Haarlem | 28 | 5 | 11 | 12 | 33:43 | -10 | 26 |
| 19 |
|
Fortuna Sittard | 28 | 6 | 8 | 14 | 32:47 | -15 | 26 |
| 20 |
|
SC Cambuur | 28 | 6 | 7 | 15 | 34:52 | -18 | 25 |
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