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| 25.01.2008 | 20:00 | BV Veendam | - | ADO Den Haag | 3:3 (0:1) | |
| 20:00 | HFC Haarlem | - | FC Emmen | 1:2 (0:0) | ||
| 20:00 | Helmond Sport | - | FC Eindhoven | 4:1 (4:0) | ||
| 20:00 | MVV | - | FC Dordrecht | 3:2 (2:0) | ||
| 20:00 | FC Zwolle | - | FC Omniworld | 1:1 (1:1) | ||
| 20:00 | AGOVV | - | SC Cambuur | 2:2 (1:0) | ||
| 20:00 | Fortuna Sittard | - | Go Ahead Eagles | 2:2 (2:1) | ||
| 20:00 | RBC Roosendaal | - | RKC Waalwijk | 0:4 (0:1) | ||
| 27.01.2008 | 14:30 | FC Volendam | - | Stormvogels Telstar | 2:0 (1:0) | |
| 18.02.2008 | 19:00 | FC Den Bosch | - | TOP Oss | 1:1 (1:1) |
| » Classement | équipe recevante | à l'extérieur | Premier tour | Second tour |
| # | Équipe | M. | G. | N. | P. | Buts | Diff. | Pts. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
RKC Waalwijk | 25 | 14 | 9 | 2 | 60:31 | 29 | 51 |
| 2 |
|
FC Volendam | 25 | 12 | 9 | 4 | 58:32 | 26 | 45 |
| 3 |
|
FC Zwolle | 25 | 12 | 9 | 4 | 47:29 | 18 | 45 |
| 4 |
|
MVV | 25 | 13 | 6 | 6 | 43:31 | 12 | 45 |
| 5 |
|
FC Den Bosch | 25 | 13 | 4 | 8 | 40:32 | 8 | 43 |
| 6 |
|
Go Ahead Eagles | 25 | 13 | 1 | 11 | 44:44 | 0 | 40 |
| 7 |
|
Helmond Sport | 25 | 11 | 5 | 9 | 34:33 | 1 | 38 |
| 8 |
|
ADO Den Haag | 25 | 10 | 7 | 8 | 41:39 | 2 | 37 |
| 9 |
|
RBC Roosendaal | 25 | 9 | 8 | 8 | 33:31 | 2 | 35 |
| 10 |
|
TOP Oss | 25 | 8 | 9 | 8 | 38:43 | -5 | 33 |
| 11 |
|
FC Emmen | 25 | 8 | 8 | 9 | 37:47 | -10 | 32 |
| 12 |
|
FC Dordrecht | 25 | 8 | 7 | 10 | 47:36 | 11 | 31 |
| 13 |
|
BV Veendam | 25 | 7 | 11 | 7 | 41:43 | -2 | 29 |
| 14 |
|
Stormvogels Telstar | 25 | 8 | 3 | 14 | 24:34 | -10 | 27 |
| 15 |
|
FC Omniworld | 25 | 5 | 10 | 10 | 39:36 | 3 | 25 |
| 16 |
|
AGOVV | 25 | 8 | 4 | 13 | 38:61 | -23 | 25 |
| 17 |
|
HFC Haarlem | 25 | 5 | 9 | 11 | 30:38 | -8 | 24 |
| 18 |
|
Fortuna Sittard | 25 | 6 | 6 | 13 | 28:42 | -14 | 24 |
| 19 |
|
SC Cambuur | 25 | 6 | 6 | 13 | 31:47 | -16 | 24 |
| 20 |
|
FC Eindhoven | 25 | 6 | 5 | 14 | 34:58 | -24 | 23 |
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