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| 13.01.2023 | 20:00 | ADO Den Haag | - | MVV | 2:1 (1:1) | |
| 20:00 | De Graafschap | - | Jong Ajax | 3:0 (1:0) | ||
| 20:00 | Helmond Sport | - | NAC Breda | 2:2 (1:1) | ||
| 20:00 | Roda JC Kerkrade | - | TOP Oss | 1:1 (0:1) | ||
| 20:00 | Telstar | - | AZ Alkmaar (J) | 1:0 (1:0) | ||
| 15.01.2023 | 12:15 | Almere City FC | - | Willem II | 1:0 (1:0) | |
| 14:30 | Heracles Almelo | - | PEC Zwolle | 0:3 (0:3) | ||
| 16.01.2023 | 20:00 | FC Utrecht (J) | - | FC Dordrecht | 0:1 (0:1) | |
| 20:00 | FC Eindhoven | - | FC Den Bosch | 4:1 (2:1) | ||
| 23.01.2023 | 20:00 | Jong PSV | - | VVV-Venlo | 1:2 (1:0) |
| » Classement | équipe recevante | à l'extérieur | Premier tour | Second tour |
| # | Équipe | M. | G. | N. | P. | Buts | Diff. | Pts. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
PEC Zwolle | 20 | 15 | 2 | 3 | 49:22 | 27 | 47 |
| 2 |
|
Heracles Almelo | 20 | 14 | 2 | 4 | 56:26 | 30 | 44 |
| 3 |
|
FC Eindhoven | 20 | 10 | 6 | 4 | 35:25 | 10 | 36 |
| 4 |
|
Almere City FC | 20 | 11 | 2 | 7 | 31:25 | 6 | 35 |
| 5 |
|
VVV-Venlo | 20 | 10 | 5 | 5 | 31:28 | 3 | 35 |
| 6 |
|
MVV | 20 | 10 | 4 | 6 | 37:33 | 4 | 34 |
| 7 |
|
AZ Alkmaar (J) | 20 | 9 | 4 | 7 | 33:25 | 8 | 31 |
| 8 |
|
Willem II | 20 | 8 | 6 | 6 | 28:22 | 6 | 30 |
| 9 |
|
Telstar | 20 | 7 | 7 | 6 | 23:28 | -5 | 28 |
| 10 |
|
De Graafschap | 20 | 7 | 4 | 9 | 31:32 | -1 | 25 |
| 11 |
|
NAC Breda | 20 | 7 | 4 | 9 | 27:34 | -7 | 25 |
| 12 |
|
Roda JC Kerkrade | 20 | 7 | 4 | 9 | 29:29 | 0 | 25 |
| 13 |
|
Jong PSV | 20 | 6 | 6 | 8 | 32:33 | -1 | 24 |
| 14 |
|
Jong Ajax | 20 | 5 | 8 | 7 | 34:36 | -2 | 23 |
| 15 |
|
ADO Den Haag | 20 | 6 | 5 | 9 | 23:31 | -8 | 23 |
| 16 |
|
FC Dordrecht | 20 | 6 | 4 | 10 | 24:36 | -12 | 22 |
| 17 |
|
Helmond Sport | 20 | 6 | 2 | 12 | 17:34 | -17 | 20 |
| 18 |
|
FC Den Bosch | 20 | 6 | 1 | 13 | 28:41 | -13 | 19 |
| 19 |
|
TOP Oss | 20 | 5 | 3 | 12 | 20:34 | -14 | 18 |
| 20 |
|
FC Utrecht (J) | 20 | 4 | 3 | 13 | 19:33 | -14 | 15 |
| Promotion | |
| Play-off |
