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|
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| 22.04.2022 | 20:00 | FC Den Bosch | - | FC Volendam | 1:2 (0:2) | |
| 20:00 | SBV Excelsior | - | AZ Alkmaar (J) | 3:3 (1:1) | ||
| 20:00 | FC Emmen | - | Roda JC Kerkrade | 2:0 (1:0) | ||
| 20:00 | TOP Oss | - | Almere City FC | 2:3 (0:2) | ||
| 20:00 | Helmond Sport | - | De Graafschap | 0:4 (0:2) | ||
| 20:00 | NAC Breda | - | FC Dordrecht | 1:2 (1:0) | ||
| 20:00 | Telstar | - | FC Eindhoven | 0:1 (0:0) | ||
| 24.04.2022 | 12:15 | ADO Den Haag | - | FC Utrecht (J) | 1:1 (1:0) | |
| 25.04.2022 | 20:00 | Jong Ajax | - | VVV-Venlo | 6:1 (1:1) | |
| 20:00 | Jong PSV | - | MVV | 2:2 (2:0) |
| » Classement | équipe recevante | à l'extérieur | Premier tour | Second tour |
| # | Équipe | M. | G. | N. | P. | Buts | Diff. | Pts. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
FC Emmen | 36 | 25 | 5 | 6 | 61:23 | 38 | 80 |
| 2 |
|
FC Volendam | 36 | 21 | 11 | 4 | 77:48 | 29 | 74 |
| 3 |
|
FC Eindhoven | 36 | 20 | 7 | 9 | 66:41 | 25 | 67 |
| 4 |
|
SBV Excelsior | 36 | 19 | 7 | 10 | 78:53 | 25 | 64 |
| 5 |
|
ADO Den Haag | 36 | 21 | 7 | 8 | 75:50 | 25 | 64 |
| 6 |
|
Roda JC Kerkrade | 36 | 17 | 12 | 7 | 73:46 | 27 | 63 |
| 7 |
|
Jong Ajax | 36 | 18 | 8 | 10 | 81:61 | 20 | 62 |
| 8 |
|
NAC Breda | 36 | 15 | 10 | 11 | 55:43 | 12 | 55 |
| 9 |
|
De Graafschap | 36 | 15 | 9 | 12 | 50:41 | 9 | 54 |
| 10 |
|
VVV-Venlo | 36 | 13 | 5 | 18 | 45:60 | -15 | 44 |
| 11 |
|
FC Den Bosch | 36 | 13 | 4 | 19 | 40:60 | -20 | 43 |
| 12 |
|
Jong PSV | 36 | 11 | 9 | 16 | 59:61 | -2 | 42 |
| 13 |
|
Almere City FC | 36 | 11 | 8 | 17 | 57:65 | -8 | 41 |
| 14 |
|
TOP Oss | 36 | 11 | 8 | 17 | 48:58 | -10 | 41 |
| 15 |
|
AZ Alkmaar (J) | 36 | 11 | 6 | 19 | 36:49 | -13 | 39 |
| 16 |
|
Telstar | 36 | 8 | 11 | 17 | 43:67 | -24 | 35 |
| 17 |
|
FC Dordrecht | 36 | 9 | 8 | 19 | 49:74 | -25 | 35 |
| 18 |
|
FC Utrecht (J) | 36 | 10 | 5 | 21 | 38:63 | -25 | 35 |
| 19 |
|
MVV | 36 | 10 | 4 | 22 | 41:75 | -34 | 34 |
| 20 |
|
Helmond Sport | 36 | 7 | 6 | 23 | 37:71 | -34 | 24 |
| Promotion | |
| Play-off | |
| Play-off |
