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| 15.03.2019 | 20:00 | SC Cambuur | - | Jong PSV | 3:1 (2:0) | |
| 20:00 | FC Utrecht (J) | - | FC Eindhoven | 1:3 (1:2) | ||
| 20:00 | FC Dordrecht | - | Roda JC Kerkrade | 3:2 (1:1) | ||
| 20:00 | MVV | - | RKC Waalwijk | 1:4 (0:1) | ||
| 20:00 | NEC Nijmegen | - | FC Den Bosch | 5:0 (3:0) | ||
| 20:00 | TOP Oss | - | Jong Ajax | 2:1 (0:0) | ||
| 20:00 | Almere City FC | - | Sparta Rotterdam | 1:3 (1:1) | ||
| 20:00 | Telstar | - | AZ Alkmaar (J) | 1:0 (0:0) | ||
| 20:00 | FC Twente | - | FC Volendam | 5:0 (4:0) | ||
| 20:00 | Helmond Sport | - | Go Ahead Eagles | 1:1 (0:1) |
| » Classement | équipe recevante | à l'extérieur | Premier tour | Second tour |
| # | Équipe | M. | G. | N. | P. | Buts | Diff. | Pts. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
FC Twente | 29 | 21 | 3 | 5 | 60:25 | 35 | 66 |
| 2 |
|
Sparta Rotterdam | 29 | 15 | 10 | 4 | 61:33 | 28 | 55 |
| 3 |
|
Go Ahead Eagles | 29 | 16 | 6 | 7 | 51:38 | 13 | 54 |
| 4 |
|
FC Den Bosch | 29 | 15 | 7 | 7 | 50:35 | 15 | 52 |
| 5 |
|
Jong PSV | 29 | 14 | 8 | 7 | 64:49 | 15 | 50 |
| 6 |
|
TOP Oss | 29 | 13 | 6 | 10 | 35:33 | 2 | 45 |
| 7 |
|
Roda JC Kerkrade | 29 | 12 | 7 | 10 | 49:43 | 6 | 43 |
| 8 |
|
MVV | 29 | 12 | 7 | 10 | 38:39 | -1 | 43 |
| 9 |
|
NEC Nijmegen | 29 | 11 | 9 | 9 | 57:46 | 11 | 42 |
| 10 |
|
Jong Ajax | 29 | 12 | 6 | 11 | 56:46 | 10 | 42 |
| 11 |
|
RKC Waalwijk | 29 | 13 | 3 | 13 | 46:43 | 3 | 42 |
| 12 |
|
SC Cambuur | 29 | 11 | 8 | 10 | 38:37 | 1 | 41 |
| 13 |
|
Almere City FC | 29 | 12 | 5 | 12 | 42:50 | -8 | 41 |
| 14 |
|
FC Eindhoven | 29 | 11 | 6 | 12 | 35:34 | 1 | 39 |
| 15 |
|
FC Volendam | 29 | 9 | 10 | 10 | 37:45 | -8 | 37 |
| 16 |
|
Telstar | 29 | 10 | 4 | 15 | 28:44 | -16 | 34 |
| 17 |
|
FC Dordrecht | 29 | 6 | 7 | 16 | 38:60 | -22 | 25 |
| 18 |
|
AZ Alkmaar (J) | 29 | 4 | 10 | 15 | 34:56 | -22 | 22 |
| 19 |
|
Helmond Sport | 29 | 2 | 9 | 18 | 25:52 | -27 | 15 |
| 20 |
|
FC Utrecht (J) | 29 | 3 | 5 | 21 | 33:69 | -36 | 14 |
| Promotion | |
| Play-off | |
| Play-off |
