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| 08.04.2016 | 20:00 | FC Volendam | - | Achilles'29 | 0:0 (0:0) | |
| 20:00 | FC Dordrecht | - | Jong PSV | 4:0 (1:0) | ||
| 20:00 | NAC Breda | - | RKC Waalwijk | 1:1 (0:0) | ||
| 20:00 | MVV | - | VVV-Venlo | 1:3 (0:0) | ||
| 20:00 | FC Eindhoven | - | Go Ahead Eagles | 0:0 (0:0) | ||
| 20:00 | FC Den Bosch | - | Telstar | 5:0 (2:0) | ||
| 20:00 | Jong Ajax | - | FC Emmen | 2:0 (0:0) | ||
| 20:00 | FC Oss | - | Almere City FC | 1:2 (0:2) | ||
| 20:00 | Helmond Sport | - | Sparta Rotterdam | 1:1 (1:1) |
| » Classement | équipe recevante | à l'extérieur | Premier tour | Second tour |
| # | Équipe | M. | G. | N. | P. | Buts | Diff. | Pts. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Sparta Rotterdam | 32 | 22 | 7 | 3 | 75:33 | 42 | 73 |
| 2 |
|
VVV-Venlo | 33 | 20 | 6 | 7 | 77:37 | 40 | 66 |
| 3 |
|
FC Eindhoven | 33 | 19 | 6 | 8 | 53:37 | 16 | 63 |
| 4 |
|
NAC Breda | 32 | 18 | 6 | 8 | 73:34 | 39 | 60 |
| 5 |
|
Go Ahead Eagles | 32 | 14 | 7 | 11 | 49:38 | 11 | 49 |
| 6 |
|
FC Emmen | 32 | 14 | 6 | 12 | 52:48 | 4 | 48 |
| 7 |
|
FC Volendam | 32 | 12 | 9 | 11 | 47:35 | 12 | 45 |
| 8 |
|
Jong Ajax | 32 | 12 | 9 | 11 | 54:52 | 2 | 45 |
| 9 |
|
Jong PSV | 32 | 11 | 9 | 12 | 45:58 | -13 | 42 |
| 10 |
|
MVV | 32 | 11 | 8 | 13 | 42:54 | -12 | 41 |
| 11 |
|
Telstar | 33 | 11 | 7 | 15 | 52:57 | -5 | 40 |
| 12 |
|
Almere City FC | 32 | 11 | 7 | 14 | 55:64 | -9 | 40 |
| 13 |
|
FC Den Bosch | 32 | 9 | 10 | 13 | 43:45 | -2 | 37 |
| 14 |
|
Helmond Sport | 32 | 9 | 9 | 14 | 46:53 | -7 | 36 |
| 15 |
|
FC Dordrecht | 33 | 10 | 6 | 17 | 41:59 | -18 | 36 |
| 16 |
|
Fortuna Sittard | 32 | 10 | 6 | 16 | 37:66 | -29 | 36 |
| 17 |
|
Achilles'29 | 32 | 9 | 8 | 15 | 37:53 | -16 | 35 |
| 18 |
|
FC Oss | 32 | 7 | 7 | 18 | 37:68 | -31 | 28 |
| 19 |
|
RKC Waalwijk | 32 | 6 | 9 | 17 | 36:60 | -24 | 27 |
| Promotion | |
| Play-off | |
| Play-off | |
| Play-off |
