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| 17.10.2021 | 14:00 | USV Hercules | - | EVV | 3:0 (0:0) | |
| 14:00 | VV Hoogland | - | VV Dongen | 0:1 (0:1) | ||
| 14:00 | Quick Den Haag | - | ADO '20 | 0:1 (0:0) | ||
| 14:00 | Blauw Geel '38 | - | OFC Oostzaan | 2:3 (1:1) | ||
| 14:00 | RKVV DEM | - | HSC'21 | 0:3 (0:0) | ||
| 14:00 | RKVV Westlandia | - | VV UNA | 0:3 (0:2) | ||
| 14:00 | Unitas Gorinchem | - | VV Gemert | 0:3 (0:1) | ||
| 14:30 | RKSV Groene Ster | - | JOS Watergraafsmeer | 1:0 (1:0) | ||
| 14:30 | OSS '20 | - | HVV Hollandia | 3:1 (1:0) |
| # | Équipe | M. | G. | N. | P. | Buts | Diff. | Pts. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
OFC Oostzaan | 9 | 7 | 1 | 1 | 20:10 | 10 | 22 |
| 2 |
|
OSS '20 | 9 | 6 | 1 | 2 | 20:12 | 8 | 18 |
| 3 |
|
VV UNA | 9 | 6 | 0 | 3 | 20:15 | 5 | 18 |
| 4 |
|
USV Hercules | 9 | 5 | 2 | 2 | 20:11 | 9 | 17 |
| 5 |
|
VV Gemert | 9 | 4 | 5 | 0 | 18:10 | 8 | 17 |
| 6 |
|
Unitas Gorinchem | 9 | 5 | 1 | 3 | 16:14 | 2 | 16 |
| 7 |
|
ADO '20 | 9 | 5 | 0 | 4 | 17:13 | 4 | 15 |
| 8 |
|
RKSV Groene Ster | 9 | 4 | 2 | 3 | 14:15 | -1 | 14 |
| 9 |
|
VV Dongen | 9 | 3 | 3 | 3 | 12:11 | 1 | 12 |
| 10 |
|
Quick Den Haag | 9 | 3 | 1 | 5 | 7:8 | -1 | 10 |
| 11 |
|
EVV | 9 | 2 | 4 | 3 | 6:10 | -4 | 10 |
| 12 |
|
Blauw Geel '38 | 9 | 3 | 1 | 5 | 12:17 | -5 | 10 |
| 13 |
|
JOS Watergraafsmeer | 9 | 3 | 2 | 4 | 14:14 | 0 | 9 |
| 14 |
|
RKVV Westlandia | 9 | 2 | 3 | 4 | 12:14 | -2 | 9 |
| 15 |
|
HVV Hollandia | 9 | 2 | 3 | 4 | 9:12 | -3 | 9 |
| 16 |
|
HSC'21 | 9 | 2 | 2 | 5 | 13:16 | -3 | 8 |
| 17 |
|
VV Hoogland | 9 | 1 | 3 | 5 | 7:19 | -12 | 6 |
| 18 |
|
RKVV DEM | 9 | 0 | 2 | 7 | 3:19 | -16 | 2 |
| Promotion | |
| Relégation | |
| Relégation |
