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| 05.09.2021 | 14:00 | USV Hercules | - | OSS '20 | 3:1 (1:0) | |
| 14:00 | VV Hoogland | - | RKVV Westlandia | 0:4 (0:3) | ||
| 14:00 | ADO '20 | - | VV UNA | 3:0 (1:0) | ||
| 14:00 | VV Dongen | - | RKVV DEM | 3:0 (1:0) | ||
| 14:00 | HVV Hollandia | - | EVV | 0:0 (0:0) | ||
| 14:00 | Quick Den Haag | - | OFC Oostzaan | 0:2 (0:1) | ||
| 14:00 | Blauw Geel '38 | - | Unitas Gorinchem | 2:1 (1:0) | ||
| 14:30 | HSC'21 | - | JOS Watergraafsmeer | 1:5 (1:3) | ||
| 14:30 | RKSV Groene Ster | - | VV Gemert | 3:3 (2:3) |
| # | Équipe | M. | G. | N. | P. | Buts | Diff. | Pts. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
OFC Oostzaan | 3 | 3 | 0 | 0 | 6:2 | 4 | 9 |
| 2 |
|
VV UNA | 3 | 2 | 0 | 1 | 6:4 | 2 | 6 |
| 3 |
|
Blauw Geel '38 | 3 | 2 | 0 | 1 | 6:5 | 1 | 6 |
| 4 |
|
JOS Watergraafsmeer | 3 | 2 | 1 | 0 | 7:2 | 5 | 5 |
| 5 |
|
OSS '20 | 3 | 2 | 0 | 1 | 8:4 | 4 | 5 |
| 6 |
|
VV Gemert | 3 | 1 | 2 | 0 | 7:6 | 1 | 5 |
| 7 |
|
RKVV Westlandia | 3 | 1 | 1 | 1 | 5:3 | 2 | 4 |
|
VV Dongen | 3 | 1 | 1 | 1 | 5:3 | 2 | 4 | |
| 9 |
|
USV Hercules | 3 | 1 | 1 | 1 | 4:3 | 1 | 4 |
| 10 |
|
RKSV Groene Ster | 3 | 1 | 1 | 1 | 7:7 | 0 | 4 |
| 11 |
|
Quick Den Haag | 3 | 1 | 1 | 1 | 2:2 | 0 | 4 |
|
Unitas Gorinchem | 3 | 1 | 1 | 1 | 2:2 | 0 | 4 | |
| 13 |
|
EVV | 3 | 1 | 1 | 1 | 3:4 | -1 | 4 |
| 14 |
|
ADO '20 | 3 | 1 | 0 | 2 | 5:7 | -2 | 3 |
| 15 |
|
VV Hoogland | 3 | 0 | 2 | 1 | 2:6 | -4 | 2 |
| 16 |
|
HVV Hollandia | 3 | 0 | 1 | 2 | 0:3 | -3 | 1 |
| 17 |
|
RKVV DEM | 3 | 0 | 1 | 2 | 0:6 | -6 | 1 |
| 18 |
|
HSC'21 | 3 | 0 | 0 | 3 | 2:8 | -6 | 0 |
| Promotion | |
| Relégation | |
| Relégation |
