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| 09.10.2021 | 14:30 | HSV Hoek | - | ODIN '59 | 0:2 (0:0) | |
| 14:30 | VV Staphorst | - | FC Lisse | 1:3 (1:1) | ||
| 14:30 | Excelsior '31 | - | AFC Ajax Zaterdag | 2:0 (1:0) | ||
| 14:30 | BVV Barendrecht | - | VV GOES | 2:2 (1:1) | ||
| 14:30 | DVS'33 | - | VVOG Harderwijk | 5:0 (1:0) | ||
| 14:30 | SteDoCo | - | VV DOVO Veenendaal | 2:0 (1:0) | ||
| 15:00 | Sportlust '46 | - | Harkemase Boys | 4:1 (0:0) | ||
| 15:00 | Ter Leede | - | Sparta Nijkerk | 1:5 (0:3) | ||
| 18:00 | VV Sint Bavo | - | ACV Assen | 0:3 (0:1) |
| # | Équipe | M. | G. | N. | P. | Buts | Diff. | Pts. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Sparta Nijkerk | 8 | 6 | 2 | 0 | 16:5 | 11 | 20 |
| 2 |
|
FC Lisse | 8 | 5 | 1 | 2 | 17:9 | 8 | 16 |
| 3 |
|
Excelsior '31 | 8 | 4 | 2 | 2 | 16:9 | 7 | 14 |
| 4 |
|
ACV Assen | 8 | 4 | 2 | 2 | 15:10 | 5 | 14 |
| 5 |
|
Sportlust '46 | 8 | 4 | 2 | 2 | 12:12 | 0 | 14 |
| 6 |
|
DVS'33 | 8 | 4 | 1 | 3 | 15:8 | 7 | 13 |
| 7 |
|
Harkemase Boys | 8 | 3 | 3 | 2 | 16:15 | 1 | 12 |
| 8 |
|
VV Staphorst | 8 | 2 | 4 | 2 | 10:7 | 3 | 10 |
| 9 |
|
AFC Ajax Zaterdag | 8 | 3 | 1 | 4 | 9:8 | 1 | 10 |
| 10 |
|
Ter Leede | 8 | 3 | 1 | 4 | 9:16 | -7 | 10 |
| 11 |
|
HSV Hoek | 8 | 2 | 3 | 3 | 14:15 | -1 | 9 |
| 12 |
|
BVV Barendrecht | 8 | 2 | 3 | 3 | 14:16 | -2 | 9 |
| 13 |
|
VV Sint Bavo | 8 | 2 | 3 | 3 | 9:12 | -3 | 9 |
| 14 |
|
VVOG Harderwijk | 8 | 2 | 3 | 3 | 12:21 | -9 | 9 |
| 15 |
|
SteDoCo | 8 | 2 | 2 | 4 | 10:10 | 0 | 8 |
| 16 |
|
ODIN '59 | 8 | 2 | 2 | 4 | 9:14 | -5 | 8 |
| 17 |
|
VV GOES | 8 | 0 | 5 | 3 | 10:16 | -6 | 5 |
| 18 |
|
VV DOVO Veenendaal | 8 | 1 | 2 | 5 | 7:17 | -10 | 5 |
| Promotion | |
| Relégation | |
| Relégation |
