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| 06.03.2021 | 14:00 | Makedonija GP | - | Sileks Kratovo | 1:0 (1:0) | |
| 07.03.2021 | 14:00 | FK Belasica | - | FK AP Brera Strumica | 0:0 (0:0) | |
| 14:00 | FK Pelister | - | FK Borec | 1:0 (1:0) | ||
| 14:00 | KF Shkupi | - | FK Rabotnički | 0:2 (0:2) | ||
| 14:00 | KF Shkëndija 79 | - | FK Renova | 0:0 (0:0) | ||
| 14:00 | Vardar Skopje | - | FC Struga | 1:1 (0:1) |
| » Classement | équipe recevante | à l'extérieur | Premier tour | Second tour |
| # | Équipe | M. | G. | N. | P. | Buts | Diff. | Pts. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
KF Shkëndija 79 | 22 | 13 | 8 | 1 | 40:14 | 26 | 47 |
| 2 |
|
KF Shkupi | 22 | 11 | 7 | 4 | 30:19 | 11 | 40 |
| 3 |
|
Makedonija GP | 22 | 11 | 5 | 6 | 34:27 | 7 | 38 |
| 4 |
|
FC Struga | 22 | 8 | 9 | 5 | 24:19 | 5 | 33 |
| 5 |
|
FK Rabotnički | 22 | 7 | 11 | 4 | 26:21 | 5 | 32 |
| 6 |
|
FK Borec | 22 | 8 | 5 | 9 | 22:23 | -1 | 29 |
| 7 |
|
FK Pelister | 22 | 7 | 7 | 8 | 22:25 | -3 | 28 |
| 8 |
|
Vardar Skopje | 22 | 6 | 9 | 7 | 28:32 | -4 | 27 |
| 9 |
|
Sileks Kratovo | 22 | 6 | 5 | 11 | 27:27 | 0 | 23 |
| 10 |
|
FK Renova | 22 | 5 | 8 | 9 | 25:32 | -7 | 23 |
| 11 |
|
FK AP Brera Strumica | 22 | 6 | 4 | 12 | 15:25 | -10 | 22 |
| 12 |
|
FK Belasica | 22 | 3 | 4 | 15 | 18:47 | -29 | 13 |
| Champions League Quali. | |
| Relégation | |
| Relégation |
