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| 03.03.2021 | 14:00 | FK AP Brera Strumica | - | Makedonija GP | 2:1 (1:0) | |
| 14:00 | FK Borec | - | FK Belasica | 2:1 (2:1) | ||
| 14:00 | FK Rabotnički | - | KF Shkëndija 79 | 0:0 (0:0) | ||
| 14:00 | FK Renova | - | Vardar Skopje | 3:0 (2:0) | ||
| 14:00 | Sileks Kratovo | - | KF Shkupi | 0:1 (0:0) | ||
| 14:00 | FC Struga | - | FK Pelister | 0:1 (0:0) |
| » Classement | équipe recevante | à l'extérieur | Premier tour | Second tour |
| # | Équipe | M. | G. | N. | P. | Buts | Diff. | Pts. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
KF Shkëndija 79 | 21 | 13 | 7 | 1 | 40:14 | 26 | 46 |
| 2 |
|
KF Shkupi | 21 | 11 | 7 | 3 | 30:17 | 13 | 40 |
| 3 |
|
Makedonija GP | 21 | 10 | 5 | 6 | 33:27 | 6 | 35 |
| 4 |
|
FC Struga | 21 | 8 | 8 | 5 | 23:18 | 5 | 32 |
| 5 |
|
FK Rabotnički | 21 | 6 | 11 | 4 | 24:21 | 3 | 29 |
| 6 |
|
FK Borec | 21 | 8 | 5 | 8 | 22:22 | 0 | 29 |
| 7 |
|
Vardar Skopje | 21 | 6 | 8 | 7 | 27:31 | -4 | 26 |
| 8 |
|
FK Pelister | 21 | 6 | 7 | 8 | 21:25 | -4 | 25 |
| 9 |
|
Sileks Kratovo | 21 | 6 | 5 | 10 | 27:26 | 1 | 23 |
| 10 |
|
FK Renova | 21 | 5 | 7 | 9 | 25:32 | -7 | 22 |
| 11 |
|
FK AP Brera Strumica | 21 | 6 | 3 | 12 | 15:25 | -10 | 21 |
| 12 |
|
FK Belasica | 21 | 3 | 3 | 15 | 18:47 | -29 | 12 |
| Champions League Quali. | |
| Relégation | |
| Relégation |
