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| 13.02.2021 | 14:00 | FK AP Brera Strumica | - | FK Rabotnički | 0:1 (0:0) | |
| 21.02.2021 | 14:00 | FK Borec | - | KF Shkupi | 0:1 (0:0) | |
| 14:00 | FK Renova | - | FK Belasica | 2:4 (0:1) | ||
| 14:00 | Sileks Kratovo | - | KF Shkëndija 79 | 1:2 (1:1) | ||
| 14:00 | FC Struga | - | Makedonija GP | 1:1 (0:0) | ||
| 14:00 | Vardar Skopje | - | FK Pelister | 2:2 (1:1) |
| » Classement | équipe recevante | à l'extérieur | Premier tour | Second tour |
| # | Équipe | M. | G. | N. | P. | Buts | Diff. | Pts. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
KF Shkëndija 79 | 19 | 12 | 6 | 1 | 38:13 | 25 | 42 |
| 2 |
|
KF Shkupi | 19 | 10 | 6 | 3 | 29:17 | 12 | 36 |
| 3 |
|
Makedonija GP | 19 | 10 | 4 | 5 | 32:25 | 7 | 34 |
| 4 |
|
FC Struga | 19 | 7 | 8 | 4 | 21:16 | 5 | 29 |
| 5 |
|
FK Rabotnički | 19 | 6 | 9 | 4 | 23:20 | 3 | 27 |
| 6 |
|
Vardar Skopje | 19 | 6 | 8 | 5 | 26:26 | 0 | 26 |
| 7 |
|
FK Borec | 19 | 7 | 4 | 8 | 20:21 | -1 | 25 |
| 8 |
|
Sileks Kratovo | 19 | 6 | 4 | 9 | 26:24 | 2 | 22 |
| 9 |
|
FK Pelister | 19 | 4 | 7 | 8 | 17:24 | -7 | 19 |
| 10 |
|
FK Renova | 19 | 4 | 7 | 8 | 21:29 | -8 | 19 |
| 11 |
|
FK AP Brera Strumica | 19 | 5 | 2 | 12 | 13:24 | -11 | 17 |
| 12 |
|
FK Belasica | 19 | 3 | 3 | 13 | 16:43 | -27 | 12 |
| Champions League Quali. | |
| Relégation | |
| Relégation |
