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| 22.09.2018 | 16:00 | UANL Tigres | - | CF Monterrey | 2:1 (0:1) | |
| 16:00 | Club Necaxa | - | Santos Laguna | 1:0 (0:0) | ||
| 17:00 | CF Pachuca | - | CD Veracruz | 2:0 (1:0) | ||
| 17:00 | Pumas UNAM | - | Lobos BUAP | 2:0 (1:0) | ||
| 19:00 | Cruz Azul | - | Club Tijuana | 1:0 (0:0) | ||
| 20:00 | Deportivo Guadalajara | - | Gallos Blancos | 2:0 (2:0) | ||
| 20:30 | Club León | - | Atlas Guadalajara | 3:1 (1:0) | ||
| 23.09.2018 | 16:00 | Deportivo Toluca | - | Puebla FC | 2:0 (1:0) |
| » Classement | équipe recevante | à l'extérieur | Premier tour | Second tour |
| 1 | |||||||||
| # | Équipe | M. | G. | N. | P. | Buts | Diff. | Pts. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
CF Pachuca | 9 | 8 | 1 | 0 | 23:2 | 21 | 25 |
| 2 |
|
Pumas UNAM | 9 | 5 | 2 | 2 | 12:6 | 6 | 17 |
| 3 |
|
Cruz Azul | 9 | 5 | 1 | 3 | 14:10 | 4 | 16 |
| 4 |
|
CF América | 8 | 5 | 1 | 2 | 12:9 | 3 | 16 |
| 5 |
|
Deportivo Toluca | 9 | 4 | 2 | 3 | 14:11 | 3 | 14 |
| 6 |
|
Club Tijuana | 9 | 4 | 1 | 4 | 17:13 | 4 | 13 |
| 7 |
|
Puebla FC | 9 | 2 | 1 | 6 | 7:20 | -13 | 7 |
| 8 |
|
CD Veracruz | 9 | 0 | 4 | 5 | 7:19 | -12 | 4 |
| 9 |
|
Lobos BUAP | 9 | 0 | 1 | 8 | 3:19 | -16 | 1 |
| 2 | |||||||||
| # | Équipe | M. | G. | N. | P. | Buts | Diff. | Pts. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Club León | 9 | 5 | 3 | 1 | 16:9 | 7 | 18 |
| 2 |
|
CF Monterrey | 9 | 4 | 3 | 2 | 21:12 | 9 | 15 |
| 3 |
|
Atlas Guadalajara | 9 | 4 | 2 | 3 | 23:17 | 6 | 14 |
| 4 |
|
Deportivo Guadalajara | 9 | 4 | 2 | 3 | 13:7 | 6 | 14 |
| 5 |
|
UANL Tigres | 9 | 3 | 4 | 2 | 10:13 | -3 | 13 |
| 6 |
|
Monarcas Morelia | 8 | 3 | 3 | 2 | 8:8 | 0 | 12 |
| 7 |
|
Santos Laguna | 9 | 2 | 3 | 4 | 13:18 | -5 | 9 |
| 8 |
|
Club Necaxa | 9 | 2 | 2 | 5 | 5:17 | -12 | 8 |
| 9 |
|
Gallos Blancos | 9 | 2 | 0 | 7 | 10:18 | -8 | 6 |
