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| 01.03.2019 | 17:00 | Pumas UNAM II | - | Cocodrilos de Tabasco | 1:0 (0:0) | |
| 17:00 | CF América II | - | Real Zamora | 1:4 (0:1) | ||
| 02.03.2019 | 03:00 | Coras de Nayarit | - | Cimarrones de Sonora II | 2:0 (1:0) | |
| 03:00 | Alacranes de Durango | - | Leones Negros II | 2:3 (1:2) | ||
| 19:15 | Deportivo Toluca II | - | Yalmakan FC | 2:1 (0:0) | ||
| 22:00 | Tuxtla FC | - | Coyotes de Tlaxcala | 1:2 (1:0) | ||
| 22:00 | Albinegros Orizaba | - | Cruz Azul Hidalgo | 4:1 (1:0) | ||
| 23:00 | Dorados UACH | - | Club Necaxa II | 1:0 (0:0) | ||
| 03.03.2019 | 00:00 | Correcaminos UAT II | - | Gavilanes de Matamoros | 2:0 (2:0) | |
| 00:00 | Pioneros de Cancún | - | Reboceros de La Piedad | 2:0 (1:0) | ||
| 00:00 | Inter Playa | - | Sporting Canamy | 0:1 (0:1) | ||
| 02:00 | Club Irapuato | - | Tuzos de la UAZ | 3:0 (1:0) | ||
| 02:00 | Pacific F. C. | - | Monarcas Morelia II | 1:1 (1:1) | ||
| 17:00 | Deportivo Guadalajara II | - | Murciélagos FC | 1:0 (1:0) | ||
| 05.03.2019 | 00:00 | Loros UCOL | - | Tepatitlán | 2:0 (1:0) | |
| 02.04.2019 | 19:00 | Tecos Fútbol Club | - | Atlético Reynosa | 2:2 (0:1) |
| » Classement | équipe recevante | à l'extérieur | Premier tour | Second tour |
| # | Équipe | M. | G. | N. | P. | Buts | Diff. | Pts. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Club Irapuato | 23 | 17 | 4 | 2 | 42:14 | 28 | 59 |
| 2 |
|
Loros UCOL | 23 | 13 | 4 | 6 | 58:25 | 33 | 49 |
| 3 |
|
Deportivo Guadalajara II | 23 | 12 | 8 | 3 | 35:23 | 12 | 48 |
| 4 |
|
Tepatitlán | 23 | 12 | 6 | 5 | 39:28 | 11 | 44 |
| 5 |
|
Murciélagos FC | 23 | 12 | 4 | 7 | 41:24 | 17 | 43 |
| 6 |
|
Club Necaxa II | 23 | 11 | 7 | 5 | 28:23 | 5 | 43 |
| 7 |
|
Tuxtla FC | 23 | 12 | 4 | 7 | 37:22 | 15 | 42 |
| 8 |
|
Atlético Reynosa | 23 | 10 | 7 | 6 | 30:17 | 13 | 41 |
| 9 |
|
Pumas UNAM II | 23 | 11 | 5 | 7 | 32:24 | 8 | 41 |
| 10 |
|
Tuzos de la UAZ | 23 | 10 | 8 | 5 | 34:28 | 6 | 40 |
| 11 |
|
Dorados UACH | 23 | 10 | 6 | 7 | 25:21 | 4 | 40 |
| 12 |
|
Coras de Nayarit | 23 | 10 | 7 | 6 | 31:25 | 6 | 39 |
| 13 |
|
Real Zamora | 23 | 11 | 4 | 8 | 31:27 | 4 | 39 |
| 14 |
|
Deportivo Toluca II | 23 | 10 | 6 | 7 | 34:30 | 4 | 38 |
| 15 |
|
Cruz Azul Hidalgo | 23 | 9 | 5 | 9 | 27:26 | 1 | 36 |
| 16 |
|
Gavilanes de Matamoros | 23 | 9 | 6 | 8 | 31:27 | 4 | 35 |
| 17 |
|
Monarcas Morelia II | 23 | 8 | 8 | 7 | 40:26 | 14 | 33 |
| 18 |
|
Inter Playa | 23 | 8 | 7 | 8 | 26:25 | 1 | 33 |
| 19 |
|
Correcaminos UAT II | 23 | 8 | 6 | 9 | 27:32 | -5 | 33 |
| 20 |
|
Coyotes de Tlaxcala | 23 | 6 | 12 | 5 | 29:26 | 3 | 32 |
| 21 |
|
Albinegros Orizaba | 23 | 8 | 5 | 10 | 19:29 | -10 | 30 |
| 22 |
|
Reboceros de La Piedad | 23 | 5 | 8 | 10 | 28:35 | -7 | 27 |
| 23 |
|
Tecos Fútbol Club | 23 | 5 | 6 | 12 | 29:37 | -8 | 26 |
| 24 |
|
Cocodrilos de Tabasco | 23 | 4 | 10 | 9 | 20:26 | -6 | 25 |
| 25 |
|
Leones Negros II | 23 | 6 | 6 | 11 | 28:37 | -9 | 25 |
| 26 |
|
Sporting Canamy | 23 | 6 | 6 | 11 | 25:42 | -17 | 25 |
| 27 |
|
Pioneros de Cancún | 23 | 4 | 10 | 9 | 22:29 | -7 | 24 |
| 28 |
|
Yalmakan FC | 23 | 4 | 8 | 11 | 24:34 | -10 | 22 |
| 29 |
|
CF América II | 23 | 3 | 10 | 10 | 24:37 | -13 | 21 |
| 30 |
|
Alacranes de Durango | 23 | 4 | 8 | 11 | 18:31 | -13 | 21 |
| 31 |
|
Pacific F. C. | 23 | 3 | 6 | 14 | 22:51 | -29 | 17 |
| 32 |
|
Cimarrones de Sonora II | 23 | 2 | 3 | 18 | 10:65 | -55 | 9 |
| Play-off | |
| Play-off | |
| Play-off | |
| Play-off | |
| Play-off | |
| Play-off | |
| Play-off | |
| Play-off | |
| Play-off | |
| Relégation |
