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| 11.01.2019 | 22:00 | Cruz Azul Hidalgo | - | Real Zamora | 2:0 (2:0) | |
| 12.01.2019 | 02:30 | Atlético Reynosa | - | Correcaminos UAT II | 1:0 (0:0) | |
| 03:00 | Murciélagos FC | - | Gavilanes de Matamoros | 3:0 (1:0) | ||
| 18:00 | Coyotes de Tlaxcala | - | Club Irapuato | 2:2 (2:2) | ||
| 18:00 | Cimarrones de Sonora II | - | Monarcas Morelia II | 3:1 (1:1) | ||
| 19:15 | Deportivo Toluca II | - | CF América II | 2:1 (1:0) | ||
| 22:00 | Albinegros Orizaba | - | Pumas UNAM II | 0:2 (0:1) | ||
| 23:00 | Dorados UACH | - | Loros UCOL | 3:0 (2:0) | ||
| 23:00 | Tepatitlán | - | Tecos Fútbol Club | 3:2 (1:1) | ||
| 23:00 | Yalmakan FC | - | Sporting Canamy | 3:0 (1:0) | ||
| 23:00 | Cocodrilos de Tabasco | - | Tuxtla FC | 0:1 (0:1) | ||
| 13.01.2019 | 00:00 | Pioneros de Cancún | - | Inter Playa | 0:0 (0:0) | |
| 03:00 | Reboceros de La Piedad | - | Tuzos de la UAZ | 2:2 (1:1) | ||
| 17:00 | Deportivo Guadalajara II | - | Pacific F. C. | 2:2 (1:1) | ||
| 18:00 | Club Necaxa II | - | Leones Negros II | 1:0 (1:0) | ||
| 15.01.2019 | 00:00 | Coras de Nayarit | - | Alacranes de Durango | 1:0 (0:0) |
| » Classement | équipe recevante | à l'extérieur | Premier tour | Second tour |
| # | Équipe | M. | G. | N. | P. | Buts | Diff. | Pts. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Club Irapuato | 16 | 12 | 3 | 1 | 29:10 | 19 | 43 |
| 2 |
|
Murciélagos FC | 16 | 10 | 3 | 3 | 31:15 | 16 | 36 |
| 3 |
|
Loros UCOL | 16 | 9 | 2 | 5 | 34:18 | 16 | 35 |
| 4 |
|
Deportivo Guadalajara II | 16 | 8 | 7 | 1 | 28:14 | 14 | 35 |
| 5 |
|
Cruz Azul Hidalgo | 16 | 9 | 3 | 4 | 25:15 | 10 | 34 |
| 6 |
|
Club Necaxa II | 16 | 8 | 7 | 1 | 19:12 | 7 | 34 |
| 7 |
|
Tuxtla FC | 16 | 9 | 3 | 4 | 29:16 | 13 | 32 |
| 8 |
|
Tepatitlán | 16 | 8 | 4 | 4 | 27:20 | 7 | 30 |
| 9 |
|
Atlético Reynosa | 16 | 7 | 4 | 5 | 20:12 | 8 | 29 |
| 10 |
|
Pumas UNAM II | 16 | 8 | 2 | 6 | 25:20 | 5 | 29 |
| 11 |
|
Coras de Nayarit | 16 | 7 | 5 | 4 | 24:19 | 5 | 28 |
| 12 |
|
Inter Playa | 16 | 7 | 4 | 5 | 22:18 | 4 | 27 |
| 13 |
|
Tuzos de la UAZ | 16 | 6 | 7 | 3 | 23:21 | 2 | 27 |
| 14 |
|
Gavilanes de Matamoros | 16 | 7 | 4 | 5 | 20:19 | 1 | 27 |
| 15 |
|
Deportivo Toluca II | 16 | 6 | 6 | 4 | 25:19 | 6 | 26 |
| 16 |
|
Coyotes de Tlaxcala | 16 | 4 | 9 | 3 | 18:17 | 1 | 23 |
| 17 |
|
Correcaminos UAT II | 16 | 5 | 5 | 6 | 16:18 | -2 | 23 |
| 18 |
|
Real Zamora | 16 | 6 | 3 | 7 | 17:21 | -4 | 23 |
| 19 |
|
Dorados UACH | 16 | 5 | 4 | 7 | 15:19 | -4 | 23 |
| 20 |
|
Tecos Fútbol Club | 16 | 4 | 4 | 8 | 22:26 | -4 | 21 |
| 21 |
|
Monarcas Morelia II | 16 | 5 | 4 | 7 | 27:20 | 7 | 20 |
| 22 |
|
Sporting Canamy | 16 | 5 | 4 | 7 | 21:29 | -8 | 20 |
| 23 |
|
Albinegros Orizaba | 16 | 5 | 4 | 7 | 8:17 | -9 | 20 |
| 24 |
|
Reboceros de La Piedad | 16 | 3 | 6 | 7 | 19:27 | -8 | 19 |
| 25 |
|
Yalmakan FC | 16 | 3 | 6 | 7 | 18:22 | -4 | 17 |
| 26 |
|
Leones Negros II | 16 | 4 | 4 | 8 | 20:26 | -6 | 17 |
| 27 |
|
Cocodrilos de Tabasco | 16 | 2 | 7 | 7 | 17:22 | -5 | 16 |
| 28 |
|
Pacific F. C. | 16 | 3 | 5 | 8 | 17:35 | -18 | 16 |
| 29 |
|
CF América II | 16 | 2 | 6 | 8 | 16:27 | -11 | 14 |
| 30 |
|
Alacranes de Durango | 16 | 2 | 6 | 8 | 8:20 | -12 | 13 |
| 31 |
|
Pioneros de Cancún | 16 | 1 | 7 | 8 | 14:25 | -11 | 12 |
| 32 |
|
Cimarrones de Sonora II | 16 | 1 | 2 | 13 | 8:43 | -35 | 5 |
| Play-off | |
| Play-off | |
| Play-off | |
| Play-off | |
| Play-off | |
| Play-off | |
| Play-off | |
| Play-off | |
| Play-off | |
| Relégation |
