 |
 |
|
|
| 02.10.2021 | 19:00 | Pumas UNAM | - | Deportivo Guadalajara | 1:0 (0:0) | |
| 03.10.2021 | 02:00 | CF Pachuca | - | Deportivo Toluca | 1:1 (1:1) | |
| 19:00 | Puebla FC | - | UANL Tigres | 0:3 (0:3) | ||
| 04.10.2021 | 00:00 | Atlético San Luis | - | Mazatlán FC | 1:1 (1:1) | |
| 05.10.2021 | 00:00 | Club Necaxa | - | Gallos Blancos | 2:0 (1:0) | |
| 02:00 | CF Monterrey | - | Club León | 3:1 (2:0) | ||
| 02:00 | CF América | - | Cruz Azul | 2:1 (0:0) | ||
| 04:00 | Club Tijuana | - | Atlas Guadalajara | 1:2 (1:0) | ||
| 04:00 | FC Juárez | - | Santos Laguna | 1:2 (0:0) |
| » Classement | équipe recevante | à l'extérieur | Premier tour | Second tour |
| # | Équipe | M. | G. | N. | P. | Buts | Diff. | Pts. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
UANL Tigres | 11 | 11 | 0 | 0 | 41:3 | 38 | 33 |
| 2 |
|
CF Monterrey | 11 | 9 | 2 | 0 | 25:5 | 20 | 29 |
| 3 |
|
Deportivo Guadalajara | 11 | 8 | 1 | 2 | 26:10 | 16 | 25 |
| 4 |
|
Santos Laguna | 11 | 7 | 3 | 1 | 30:14 | 16 | 24 |
| 5 |
|
CF América | 11 | 7 | 3 | 1 | 22:9 | 13 | 24 |
| 6 |
|
Atlas Guadalajara | 11 | 5 | 3 | 3 | 16:13 | 3 | 18 |
| 7 |
|
Club Tijuana | 11 | 4 | 3 | 4 | 13:13 | 0 | 15 |
| 8 |
|
Pumas UNAM | 11 | 3 | 5 | 3 | 11:10 | 1 | 14 |
| 9 |
|
Cruz Azul | 11 | 4 | 2 | 5 | 9:18 | -9 | 14 |
| 10 |
|
Club Necaxa | 11 | 4 | 2 | 5 | 10:22 | -12 | 14 |
| 11 |
|
Gallos Blancos | 11 | 2 | 4 | 5 | 12:15 | -3 | 10 |
| 12 |
|
CF Pachuca | 11 | 2 | 4 | 5 | 14:19 | -5 | 10 |
| 13 |
|
Puebla FC | 11 | 3 | 1 | 7 | 13:21 | -8 | 10 |
| 14 |
|
Deportivo Toluca | 11 | 2 | 3 | 6 | 10:18 | -8 | 9 |
| 15 |
|
Club León | 11 | 2 | 3 | 6 | 13:22 | -9 | 9 |
| 16 |
|
Atlético San Luis | 11 | 1 | 4 | 6 | 7:24 | -17 | 7 |
| 17 |
|
FC Juárez | 11 | 1 | 2 | 8 | 6:22 | -16 | 5 |
| 18 |
|
Mazatlán FC | 11 | 0 | 3 | 8 | 5:25 | -20 | 3 |
| Play-off |
