 |
 |
|
|
| 26.10.2021 | 12:00 | FC Sfîntul Gheorghe | - | Victoria Bardar | 1:0 | |
| 12:00 | CS Petrocub | - | Olimp Comrat | 6:0 | ||
| 12:00 | Spartanii Sportul | - | Dinamo-Auto | 1:3 | ||
| 14:00 | FC Bălţi | - | FC Cahul 2005 | 3:0 | ||
| 27.10.2021 | 12:00 | FC Floreşti | - | FC Sîngerei | 3:1 | |
| 12:00 | Speranța Drochia | - | FC Zimbru | 1:4 | ||
| 14:00 | FC Milsami | - | FCM Ungheni | 5:1 | ||
| 14:00 | FC Sheriff | - | FC Saxan | 6:0 |
