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| H (Match allé) | FC Edineţ | - | FC Milsami | 1:3 | ||
| R (match retour) | FC Milsami | - | FC Edineţ | 6:1 | ||
| H (Match allé): 25.06.2019 17:00 | R (match retour): 05.07.2019 18:00 | vainqueur: FC Milsami | ||||
| H (Match allé) | Speranţa Nisporeni | - | Speranța Drochia | 6:1 | ||
| R (match retour) | Speranța Drochia | - | Speranţa Nisporeni | 0:3 | ||
| H (Match allé): 25.06.2019 17:00 | R (match retour): 05.07.2019 17:00 | vainqueur: Speranţa Nisporeni | ||||
| H (Match allé) | FC Sheriff | - | FC Real Sireți | 12:0 | ||
| R (match retour) | FC Real Sireți | - | FC Sheriff | 0:15 | ||
| H (Match allé): 25.06.2019 18:00 | R (match retour): 05.07.2019 18:00 | vainqueur: FC Sheriff | ||||
| H (Match allé) | CS Petrocub | - | FC Tighina | 7:0 | ||
| R (match retour) | FC Tighina | - | CS Petrocub | 0:2 | ||
| H (Match allé): 25.06.2019 19:00 | R (match retour): 05.07.2019 17:00 | vainqueur: CS Petrocub | ||||
| H (Match allé) | FC Sfîntul Gheorghe | - | FCM Ungheni | 1:0 | ||
| R (match retour) | FCM Ungheni | - | FC Sfîntul Gheorghe | 0:2 | ||
| H (Match allé): 26.06.2019 17:00 | R (match retour): 06.07.2019 17:00 | vainqueur: FC Sfîntul Gheorghe | ||||
| H (Match allé) | FC Codru Lozova | - | Victoria Bardar | 7:1 | ||
| R (match retour) | Victoria Bardar | - | FC Codru Lozova | 0:3 | ||
| H (Match allé): 26.06.2019 17:00 | R (match retour): 05.07.2019 17:00 | vainqueur: FC Codru Lozova | ||||
| H (Match allé) | Sporting Trestieni | - | FC Zimbru | 2:4 | ||
| R (match retour) | FC Zimbru | - | Sporting Trestieni | 5:1 | ||
| H (Match allé): 26.06.2019 17:00 | R (match retour): 07.07.2019 17:00 | vainqueur: FC Zimbru | ||||
| H (Match allé) | Dinamo-Auto | - | FC Maiak Chirsova | 8:0 | ||
| R (match retour) | FC Maiak Chirsova | - | Dinamo-Auto | 0:3 | ||
| H (Match allé): 26.06.2019 17:00 | R (match retour): 07.07.2019 17:00 | vainqueur: Dinamo-Auto | ||||
