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| 11.09.2022 | 15:00 | Afragolese | - | Cavese | 1:2 | |
| 15:00 | Team Altamura | - | Gladiator | 3:1 | ||
| 15:00 | ASG Nocerina | - | FC Francavilla | 1:1 | ||
| 15:00 | SS Barletta Calcio | - | Sporting Fulgor Molfetta | 1:0 | ||
| 15:00 | Brindisi | - | US Bitonto | 4:1 | ||
| 15:00 | Casarano | - | FBC Gravina | 1:0 | ||
| 15:00 | Lavello | - | ASD Martina Calcio | 1:2 | ||
| 15:00 | Matera Calcio | - | ACD Nardò | 0:1 | ||
| 15:00 | Puteolana Internapoli | - | Città di Fasano | 1:1 |
| » Classement | équipe recevante | à l'extérieur | Premier tour | Second tour |
| # | Équipe | M. | G. | N. | P. | Buts | Diff. | Pts. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Brindisi | 2 | 2 | 0 | 0 | 6:1 | 5 | 6 |
| 2 |
|
ACD Nardò | 2 | 2 | 0 | 0 | 5:1 | 4 | 6 |
| 3 |
|
Casarano | 2 | 2 | 0 | 0 | 5:2 | 3 | 6 |
| 4 |
|
Cavese | 2 | 2 | 0 | 0 | 3:1 | 2 | 6 |
| 5 |
|
Città di Fasano | 2 | 1 | 1 | 0 | 5:2 | 3 | 4 |
| 6 |
|
Team Altamura | 2 | 1 | 0 | 1 | 3:2 | 1 | 3 |
| 7 |
|
Matera Calcio | 2 | 1 | 0 | 1 | 4:4 | 0 | 3 |
| 8 |
|
Gladiator | 2 | 1 | 0 | 1 | 3:3 | 0 | 3 |
| 9 |
|
ASD Martina Calcio | 2 | 1 | 0 | 1 | 4:5 | -1 | 3 |
| 10 |
|
SS Barletta Calcio | 2 | 1 | 0 | 1 | 1:2 | -1 | 3 |
| 11 |
|
ASG Nocerina | 2 | 0 | 2 | 0 | 2:2 | 0 | 2 |
| 12 |
|
Afragolese | 2 | 0 | 1 | 1 | 3:4 | -1 | 1 |
| 13 |
|
FBC Gravina | 2 | 0 | 1 | 1 | 1:2 | -1 | 1 |
| 14 |
|
FC Francavilla | 2 | 0 | 1 | 1 | 1:3 | -2 | 1 |
| 15 |
|
US Bitonto | 2 | 0 | 1 | 1 | 3:6 | -3 | 1 |
| 16 |
|
Puteolana Internapoli | 2 | 0 | 1 | 1 | 2:5 | -3 | 1 |
| 17 |
|
Sporting Fulgor Molfetta | 2 | 0 | 0 | 2 | 3:5 | -2 | 0 |
| 18 |
|
Lavello | 2 | 0 | 0 | 2 | 2:6 | -4 | 0 |
| Promotion | |
| Play-off | |
| Relégation | |
| Relégation |
